Results 61 to 70 of about 6,691 (210)

Formyl-methionine as a degradation signal at the N-termini of bacterial proteins [PDF]

, 2015
In bacteria, all nascent proteins bear the pretranslationally formed N-terminal formyl-methionine (fMet) residue. The fMet residue is cotranslationally deformylated by a ribosome-associated deformylase.
Hwang, Cheol-Sang, Piatkov, Konstantin, Varshavsky, Alexander, Vu, Tri   +3 more
core   +3 more sources

Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti [PDF]

, 2010
The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa.
Becker, Jorg D., Cosme, Ana M., Mata, Marcia F., Medeiros, Joao M C., Moreira, Leonilde M., Santos, Mario R.   +5 more
core   +3 more sources

Citrullination in Tumor Metastasis, Inside and Outside the Cells

Cancer Science, Volume 116, Issue 12, Page 3239-3249, December 2025.
ABSTRACT Tumor metastasis remains a poor prognosis because it occurs in all tissues and is difficult to diagnose or prevent before metastatic tumor nodules form. Metastasis is a multi‐step process involving tumor cells, bone marrow‐derived cells, and tissue resident cells, making it a biological three‐body problem.
Takeshi Tomita, Priyanka Sharma, Sachie Hiratsuka   +2 more
wiley   +1 more source

Effect of cytidine‐5′‐monophosphate on peptidyl transferase activity [PDF]

FEBS Letters, 1975
The transfer reaction with pA-fMet as a donor substrate is strongly stimulated by CMP, whereas the transfer reaction with CpApCpCpA-acLeu as a donor substrate is inhibited by CMP. These results indicate that the donor site of peptidyl transferase contains specific binding sites for the terminal adenosine and for the cytidylic acid residue in the ...
openaire   +2 more sources

Amino acid-dependent stability of the acyl linkage in aminoacyl-tRNA. [PDF]

, 2014
Aminoacyl-tRNAs are the biologically active substrates for peptide bond formation in protein synthesis. The stability of the acyl linkage in each aminoacyl-tRNA, formed through an ester bond that connects the amino acid carboxyl group with the tRNA ...
,, Chang, Angela Y, Hou, Ya-Ming, Kozlowski, Marisa C, Peacock, Jacob R, Walvoord, Ryan R   +5 more
core   +2 more sources

Target of rapamycin signaling in pea embryos is dependent on glutamine but detached from seed storage protein biosynthesis

New Phytologist, Volume 248, Issue 6, Page 2833-2849, December 2025.
Summary Target of rapamycin (TOR) kinase is the hub of a eukaryotic master signaling network that integrates nutritional and hormonal signals into cellular activities. Most studies on TOR in plants have focused on seedlings, where TOR is most responsive to light and sucrose.
Brendan M. O'Leary, Suvi Honkanen, Vinti Kumari, Christoph Rampitsch, Eiji Nambara, A. Harvey Millar   +5 more
wiley   +1 more source

Proteins involved in embryo-maternal interaction around the signalling of maternal recognition of pregnancy in the horse [PDF]

, 2018
During maternal recognition of pregnancy (MRP), a conceptus-derived signal leads to the persistence of the corpus luteum and the maintenance of gestation. In the horse, the nature of this signal remains to be elucidated.
De Lange, Valérie, Deforce, Dieter, Govaere, Jan, Peelman, Luc, Roels, Kim, Smits, Katrien, Van de Velde, Margot, Van Nieuwerburgh, Filip, Van Soom, Ann, Van Steendam, Katleen, Ververs, Cyrillus, Willems, Sander   +11 more
core   +3 more sources

Adaptation Mechanisms in the Evolution of Moss Defenses to Microbes [PDF]

, 2017
The tri-colored bat (Perimyotis subflavus) has declined severely across its range since 2006 due to white nose syndrome, a fungal disease causing massive bat mortality in North America.
Inés Ponce de León, Marcos Montesano
core   +3 more sources

The effect of gougerotin analogues on ribosomal peptidyl transferase

FEBS Letters, 1971
1. Introduction Gougerotin (I), a dipeptidyl pyrimidine nucleoside antibiotic, has been found to specifically inhibit the step of protein biosynthesis which is catalyzed by ribosomal peptidyl transferase [l-S] . Since three gougerotin analogues have been synthesized recently [6] , 1-[3(sarcosyl-D-seryl-)amino3-deoxy$-D-gluco- pyranosyl-)uracil (II, cf.
Černá, J., Lichtenthaler, F.W., Rychlík, I.   +2 more
openaire   +2 more sources

Epigenetics and the estrogen receptor [PDF]

, 2006
The position effect variegation in Drosophila and Schizosaccharomyces pombe, and higher-order chromatin structure regulation in yeast, is orchestrated by modifier genes of the Su(var) group, (e.g., histone deacetylases ([HDACs]), protein phosphatases ...
Bautista S., Bouras T., C. WANG, Cui Y., Dreijerink K.M., Fu M., Fu M., Fu M., Fu M., Fu M., Fu M., Fu M., Fu M., Fu M., Fuqua S.A., Girault I., Hanstein B., Hortobagyi G.N., Hulit J., J. E LEADER, Ju B.G., Kawai H., Kenny F.S., Kim M.Y., Knights C.D., Kraus W.L., Kraus W.L., Kurebayashi J., Leader J.E., Li Z., M. FU, Macaluso M., Michalides R., Paik W.K., R. G PESTELL, Sakamaki T., Sharma D., V. M POPOV, Wang C., Wang C., Wang C., Wang C., Wang C., Wang X., Westwick J.K., Yan P.S., Yang X., Zwijsen R.M.L.   +47 more
core   +2 more sources