Bone Research, 2023 Given afferent functions, sensory nerves have recently been found to exert efferent effects and directly alter organ physiology. Additionally, several studies have highlighted the indirect but crucial role of sensory nerves in the regulation of the ...
Junqin Li +20 more
doaj +1 more source
Circular RNAs in Clear Cell Renal Cell Carcinoma: Their Microarray-Based Identification, Analytical Validation, and Potential Use in a Clinico-Genomic Model to Improve Prognostic Accuracy [PDF]
, 2019 Circular RNAs (circRNAs) may act as novel cancer biomarkers. However, a genome-wide evaluation of circRNAs in clear cell renal cell carcinoma (ccRCC) has yet to be conducted. Therefore, the objective of this study was to identify and validate circRNAs in
Erbersdobler, Andreas +9 more
core +2 more sources
Role of Periplasmic Peptidylprolyl Isomerases in Salmonella enterica Serovar Typhimurium Virulence [PDF]
Infection and Immunity, 2003 ABSTRACT FkpA is a peptidylprolyl isomerase whose expression is regulated by the alternative sigma factor, sigma factor E (σ E ). In contrast to the results of a previous report, inactivation of fkpA was found to have only a minor effect on the ability of Salmonella ...
Humphreys, Sue +5 more
openaire +3 more sources
Cyclophilin J limits inflammation through the blockage of ubiquitin chain sensing
Nature Communications, 2018 Nuclear factor-kappa B (NF-κB) signaling is regulated by ubiquitin to maintain immune homeostasis. Here the authors show that a peptidylprolyl isomerase, CYPJ, blocks TAB2/3 or LUBAC ubiquitin chain sensing and suppress NF-κB activation, with CYPJ ...
Chunjie Sheng +8 more
doaj +1 more source
Introduction to Peptidyl-Prolyl cis/trans Isomerase (PPIase) Series
Biomolecules, 2019 About 30 years after the discovery of peptidyl-prolyl cis/trans isomerases (PPIases), research on this group of proteins has become somewhat calmer than it used to be, but it still generates lots of interest [...]
Andrzej Galat
doaj +1 more source
Proteomic responses reveal the differential effects induced by cadmium in mussels Mytilus galloprovincialis at early life stages [PDF]
, 2016 Cadmium (Cd) has become an important metal contaminant and posed severe risk on the organisms in the coastal environments of the Bohai Sea. Marine mussel Mytilus galloprovincialis is widely distributed along the Bohai coast and consumed as seafood by ...
Ji, CL +6 more
core +1 more source
FKBP51 and FKBP52 in signaling and disease [PDF]
, 2011 FKBP51 and FKBP52 are diverse regulators of steroid hormone receptor signaling, including receptor maturation, hormone binding and nuclear translocation.
Cox, Marc B. +4 more
core +2 more sources
Identification of heat shock protein70-2 and protamine-1 mRNA, proteins, and analyses of their association with fertility using frozen-thawed sperm in Madura bulls [PDF]
Animal Bioscience, 2023 Objective This study aims to identify heat shock protein70-2 (HSP70-2) and protamine-1 (PRM1) mRNA and protein in Madura bull sperm and demonstrate their relation as bull fertility biomarkers. Methods The Madura bull fertility rates were grouped based on
Zulfi Nur Amrina Rosyada +6 more
doaj +1 more source
Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β. [PDF]
, 2016 Mutations in human CLC-1 chloride channel are associated with the skeletal muscle disorder myotonia congenita. The disease-causing mutant A531V manifests enhanced proteasomal degradation of CLC-1.
Chen, Shu-Ching +7 more
core +1 more source
Peptidylprolyl isomerase A governs TARDBP function and assembly in heterogeneous nuclear ribonucleoprotein complexes [PDF]
Brain, 2015 Peptidylprolyl isomerase A (PPIA), also known as cyclophilin A, is a multifunctional protein with peptidyl-prolyl cis-trans isomerase activity. PPIA is also a translational biomarker for amyotrophic lateral sclerosis, and is enriched in aggregates isolated from amyotrophic lateral sclerosis and frontotemporal lobar degeneration patients.
Eliana, Lauranzano +12 more
openaire +2 more sources