Results 131 to 140 of about 795,318 (319)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Nursing-Home Care Quality Perceived Levels from Patients and Caregivers: An Explanatory Study
, 2023 Elsa Vitale,1 Rocco Mea,2 Yun-Chen Chang3,4 1Centre of Mental Health Modugno, Local Health Authority Bari, Bari, Italy; 2Cardiovascular Department, San Carlo Hospital, Potenza, Italy; 3School of Nursing and Graduate Institute of Nursing, China Medical ...
Vitale E, Mea R, Chang YC
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BuildingsCurrently, coordinated development in terms of perceived urban quality and function has become a key problem. However, there is an imbalance between the street environment and urban amenities.
Yumeng Meng +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A Rasch Analysis of a Self-Perceived Change in Quality of Life Scale in Patients with Mild Stroke
, 2009 A Rasch analysis was used to assess the unidimensionality and appropriateness of the scoring level of a 13-item self- perceived change in quality of life scale (CQOL) for stroke patients.
林昭宏;王文中;許清芳;盧成皆;薛漪平;謝清麟 +1 more
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Путеводитель предпринимателя, 2020 According to tendencies of development of marketing branding becomes the most effective remedy of ensuring competitive advantages of the company today.
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2015 Gudmund Grønhaug,1 Jon Hagfors,2 Ingebjørg Borch,2 Nina Østerås,1 Kåre Birger Hagen11National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, 2Norwegian Rheumatism Association, Oslo ...
Hagfors J +4 more
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Impact of automatic region-of-interest coding\ud on perceived quality in mobile video
, 2017 At present, the most reliable method to obtain end-user perceived quality is through subjective tests. In this paper, the impact of automatic region-of-interest (ROI) coding on perceived quality of mobile video is investigated.
Himawan, Ivan +2 more
core +1 more source