Results 161 to 170 of about 51,558 (279)

Avoidance of MAIT cells is an essential determinant of <i>Listeria</i> monocytogenes pathogenesis. [PDF]

open access: yesProc Natl Acad Sci U S A
Rivera-Lugo R   +8 more
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

open access: yes
Transfusion, EarlyView.
Thane Kubik   +2 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

open access: yesVIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang   +6 more
wiley   +1 more source

Epithelial YPEL3 Modulates CD8+ T‐Cell Infiltration and Tumor Progression Through CREB1–CXCL16 Signaling in HNSCC

open access: yesCancer Science, Volume 117, Issue 8, Page 2132-2151, August 2026.
YPEL3 functions as a tumor suppressor in HNSCC by inhibiting tumor progression and promoting apoptosis. Mechanistically, it enhances epithelial–immune crosstalk through the CREB1‐mediated CXCL16–CXCR6 axis, facilitating CD8+ T‐cell infiltration and highlighting its potential as a prognostic biomarker and immunotherapy target.
Yalun Li   +7 more
wiley   +1 more source

A Case of a Novel Perforin Gene Variant in Severe Familial Hemophagocytic Lymphohistiocytosis Type 2 (FHL2). [PDF]

open access: yesCase Rep Hematol
Yamauchi H   +13 more
europepmc   +1 more source

Structure of perforine and haplophyllidine [PDF]

open access: yesChemistry of Natural Compounds, 1967
Z. Sh. Faizutdinova   +2 more
openaire   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

open access: yesEuropean Journal of Haematology, Volume 117, Issue 2, Page 481-491, August 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida   +7 more
wiley   +1 more source

Clinical, biological and cytometric characteristics of two patients with a homozygous A91V<i>PRF1</i> mutation. [PDF]

open access: yesClin Transl Immunology
Perrard N   +12 more
europepmc   +1 more source

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