Results 141 to 150 of about 22,988 (259)

Clazosentan Affects Temporal Profile of Endothelin-A Expression in Macro- and Microcirculation after Subarachnoid Hemorrhage. [PDF]

Neurol Med Chir (Tokyo)
Zheng Y, Kawabori M, Fujioka Y, Gotoh S, Tatezawa R, Ikeda T, Honda T, Nakahara Y, Yoshie E, Li Z, Ohba Y, Fujimura M.   +11 more
europepmc   +1 more source

Morphological and transcriptomic change of brain pericytes by lipopolysaccharide treatment. [PDF]

Front Neural Circuits
Asai T, Yonezu Y, Uyeda A, Watanabe H, Suzuki T, Misawa H, Muramatsu R.   +6 more
europepmc   +1 more source

Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) arises from dysregulated interactions between nutrient delivery, adipose tissue lipid handling and liver lipid metabolism, which collectively coalesce to drive inflammatory signalling leading to metabolic dysfunction‐associated steatohepatitis (MASH) and fibrosis. Recent clinical
Evangelia E. Tsakiridis, Gregory R. Steinberg   +1 more
wiley   +1 more source

Vascular remodelling and fibrotic changes in the joint capsule during periprosthetic knee infections. [PDF]

Bone Joint Res
Qiao R, Mehl J, Qi B, Sistemich E, Fan W, Kirschbaum S, Donner S, Thiele M, Jahn D, Gwinner C, Duda G, Perka CF, Kienzle A.   +12 more
europepmc   +1 more source

Peril in perishing pericytes [PDF]

Journal of the National Cancer Institute, 2015
openaire   +2 more sources

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

From Cerebrovascular Injury to Vascular Cognitive Impairment and Dementia: Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles. [PDF]

Biomedicines
Sigdel S, Sawant H, Yu BX, Chen A, Albalawy R, Wang J.   +5 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Endothelial UNC5B regulates blood‑retinal barrier homeostasis. [PDF]

Int J Mol Med
Yao Y, Wang S, Li J, Jin Q, Chen Z, Jiang Q, Li K.   +6 more
europepmc   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

The FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto, Gergő Porkoláb, Natalie Hudson, Jeffrey O'Callaghan, Nicole Hanley, Conor Delaney, Mária A. Deli, Peter Westenskow, Matthew Campbell   +8 more
wiley   +1 more source