Results 151 to 160 of about 22,988 (259)

Where and how do leukocytes stall in retinal microcirculation: A spatiotemporal analysis with a focus on junctions and pericytes. [PDF]

J Cereb Blood Flow Metab
Başaran MD, Cakir-Aktas C, Sever-Bahcekapili M, Dalkara T, Erdener ŞE.   +4 more
europepmc   +1 more source

Beyond the chaos: How architecture structures tumour biology

The FEBS Journal, EarlyView.
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner, Catrin Lutz, Stefan Prekovic, Hendrik A. Messal   +3 more
wiley   +1 more source

Development of the blood-brain barrier. [PDF]

Development
Gastfriend BD, Daneman R.
europepmc   +1 more source

Vaginal Microbiota and Ovarian Cancer: A New Frontier in Immunomodulation and Diagnosis

Immunology, EarlyView.
Microbial imbalance, dysbiosis, plays a role in ovarian carcinogenesis by interacting with the immune system and altering inflammatory pathways, notably Th17 pathways. In contrast, eubiosis, characterised by Lactobacillus dominance, protects against infections and maintains hormone metabolism.
Wafa Babay, Mariem Garci, Ahmed Baligh Laaribi, Nabil Mathlouthi, Imene Ouzari   +4 more
wiley   +1 more source

From origins to nomenclature: illuminating the landscape of CNS fibroblasts and fibroblast-like cells. [PDF]

Acta Neuropathol Commun
Lin J, Liao K, Lewandowski SA.
europepmc   +1 more source

Intra‐Tissue Bacteriome and Cellular Profiles in Periodontal Granulation Tissue From Osseous Defects and Extraction Sockets

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng, Tianle Li, Tsz Yung Wong, Beibei Chen, Chongshan Liao, Xun Ding, Hui Chen, Wei Qiao, George Pelekos, Lijian Jin   +9 more
wiley   +1 more source

Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis. [PDF]

Gut
Wang S, Ye G, Xu X, Lin Y, Li X, Zhang Z, Qi M, Tan L, Cheng M, Zhang H, Pan J, Lin C, Huang D, Deng R, Li X, Wang G, Qiu S, Chu X, Chen Y, Zeng H, Zhang J, Wang C, Shuai H, Shi C, Yuan X, Cao Y, Chen M, Huang M, Ye W, Zhang D.   +29 more
europepmc   +1 more source

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

Journal of Diabetes Investigation, EarlyView.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang, Zixu Huang, Xiaohui Kuang, Yali Nan, Zhiwen Zhang, Zongming Song   +5 more
wiley   +1 more source

The stem cell within the vessel wall: multipotent pericytes modulating β-cell function and diabetic complications. [PDF]

Stem Cell Res Ther
Bi H, Ma R, Chen Z, Wang Y, Ding X.
europepmc   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

Journal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads, Megan H. Hagenauer, Jinglin Xiong, Erin Hernandez, Duy Manh Nguyen, Annaka Saffron, Elizabeth Flandreau, Stanley Watson Jr., Huda Akil   +8 more
wiley   +1 more source