Results 141 to 150 of about 106,411 (380)

Integrating the inputs that shape pancreatic islet hormone release. [PDF]

open access: yes, 2019
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core  

The tunica adventitia of human arteries and veins as a source of mesenchymal stem cells [PDF]

open access: yes, 2011
We previously demonstrated that human pericytes, which encircle capillaries and microvessels, give rise in culture to genuine mesenchymal stem cells (MSCs). This raised the question as to whether all MSC are derived from pericytes.
Bin Sun   +8 more
core   +1 more source

Pericytes in the disease spotlight

open access: yesTrends in Cell Biology, 2023
Hielke van Splunder   +3 more
semanticscholar   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

CD248 Regulates Wnt Signaling in Pericytes to Promote Angiogenesis and Tumor Growth in Lung Cancer [PDF]

open access: bronze, 2022
Chia‐Lun Hong   +7 more
openalex   +1 more source

Metabolic syndrome and the immunological affair with the blood-brain barrier [PDF]

open access: yes, 2015
Copyright © 2015 Mauro, De Rosa, Marelli-Berg and Solito. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
De Rosa, V   +3 more
core   +1 more source

Pericytes on the move [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2013
Pericytes were originally discovered more than100 years ago as contractile cells surrounding the endothelial cells of small blood vessels. Anatomists have later on strictly defined pericytes as cells sharing a basal membrane with the endothelium.
openaire   +3 more sources

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

Interactions between Beta-Amyloid and Pericytes in Alzheimer’s Disease

open access: yesFrontiers in Bioscience-Landmark
Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder characterized by aberrant amyloid precursor protein (APP) cleavage, pathological aggregations of beta-amyloid (Aβ) that make up Aβ plaques and hyperphosphorylation of Tau ...
You-Yue Li   +3 more
doaj   +1 more source

Occlusion of retinal capillaries caused by glial cell proliferation in chronic ocular inflammation [PDF]

open access: yes, 2015
The inner blood-retinal barrier is a gliovascular unit in which glial cells surround capillary endothelial cells and regulate retinal capillaries by paracrine interactions.
Artico, Marco   +8 more
core   +2 more sources

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