Results 201 to 210 of about 86,775 (289)

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

open access: yesJournal of Diabetes Investigation, EarlyView.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang   +5 more
wiley   +1 more source

A Meta‐Analysis of the Effects of Acute Sleep Deprivation on the Cortical Transcriptome in Rodent Models

open access: yesJournal of Sleep Research, EarlyView.
How does sleep deprivation affect the brain? We performed a meta‐analysis of publicly available transcriptional profiling datasets characterising the effects of sleep deprivation on cortical gene expression (n = 293 mice, 16,290 genes) and validated our results in an independent sample (n = 222 mice).
Cosette A. Rhoads   +8 more
wiley   +1 more source

Single-cell RNA sequencing analysis of bone cancer pain model induced by Lewis lung cancer cells in male mice. [PDF]

open access: yesAnn Med
Zhou Q   +8 more
europepmc   +1 more source

Bleomycin electrosclerotherapy for kaposiform hemangioendothelioma with Kasabach–Merritt phenomenon in an adult

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Jakob Veeser   +11 more
wiley   +1 more source

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang   +9 more
wiley   +1 more source

A biomimetic senotherapy replenishing MAT2A promotes wound regeneration in preclinical models. [PDF]

open access: yesNat Commun
Lv D   +15 more
europepmc   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

open access: yesPhotochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew   +3 more
wiley   +1 more source

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