Results 151 to 160 of about 2,231 (191)

The Perineuronal Net Protein Brevican Acts in Nucleus Accumbens Parvalbumin-Expressing Interneurons of Adult Mice to Regulate Excitatory Synaptic Inputs and Motivated Behaviors. [PDF]

Biol Psychiatry
Hazlett MF, Hall VL, Patel E, Halvorsen A, Calakos N, West AE.   +5 more
europepmc   +1 more source

Timing of Methamphetamine Exposure during Adolescence Differentially Influences Parvalbumin and Perineuronal Net Immunoreactivity in the Medial Prefrontal Cortex of Female, but Not Male, Rats.

Dev Neurosci
Brinks AS, Carrica LK, Tagler DJ, Gulley JM, Juraska JM.   +4 more
europepmc   +1 more source

Modifications of perineuronal nets to regulate plasticity

, 2018
openaire   +1 more source

Loss of Perineuronal Net in ME7 Prion Disease [PDF]

Journal of Neuropathology and Experimental Neurology, 2008
NoMicroglial activation and behavioral abnormalities occur before neuronal loss in experimental murine prion disease; the behavioral changes coincide with a reduction in synaptic plasticity.
Seth Love, Samar Betmouni, Love Seth
exaly   +5 more sources

Perineuronal net degradation in epilepsy [PDF]

Epilepsia, 2015
SummaryObjectiveWe previously reported loss of perineuronal net (PN) immunohistochemical staining around parvalbumin‐positive interneurons in the hippocampus of rats after an episode of status epilepticus (SE). We hypothesized that the loss of thePNcould alter seizure susceptibility and that matrix metalloproteinases (MMPs) were candidates for ...
Elyse K Rankin-Gee, Esther Baranov, Stephanie L Rogers   +2 more
exaly   +3 more sources

Connexin Hemichannel Mimetic Peptide Attenuates Cortical Interneuron Loss and Perineuronal Net Disruption Following Cerebral Ischemia in Near-Term Fetal Sheep

International Journal of Molecular Sciences, 2020
Perinatal hypoxia-ischemia is associated with disruption of cortical gamma-aminobutyric acid (GABA)ergic interneurons and their surrounding perineuronal nets, which may contribute to persisting neurological deficits.
Joanne O Davidson, Robert Galinský, Guido Wassink   +2 more
exaly   +2 more sources

An Extracellular Perspective on CNS Maturation: Perineuronal Nets and the Control of Plasticity [PDF]

International Journal of Molecular Sciences, 2021
During restricted time windows of postnatal life, called critical periods, neural circuits are highly plastic and are shaped by environmental stimuli. In several mammalian brain areas, from the cerebral cortex to the hippocampus and amygdala, the closure
Daniela Carulli, Joost Verhaagen, Carulli Daniela   +2 more
exaly   +2 more sources

Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican [PDF]

Neuron, 2017
Activity-dependent neuronal plasticity is a fundamental mechanism through which the nervous system adapts to sensory experience. Several lines of evidence suggest that parvalbumin (PV+) interneurons are essential in this process, but the molecular ...
Emilia Favuzzi, André Marques-Smith, Ruben Deogracias   +2 more
exaly   +2 more sources

Motor recovery through perineuronal net modulation in a Parkinson’s disease mouse model

Brain
International audiencePerineuronal nets are specialized extracellular matrix structures forming preferentially around parvalbumin interneurons to regulate plasticity.
Alain Prochiantz, Ariel A Di Nardo, Prochiantz Alain   +2 more
exaly   +2 more sources

Perineuronal net digestion with chondroitinase restores memory in mice with tau pathology [PDF]

Experimental Neurology, 2015
Alzheimer's disease is the most prevalent tauopathy and cause of dementia. We investigate the hypothesis that reactivation of plasticity can restore function in the presence of neuronal damage resulting from tauopathy. We investigated two models with tau
Sujeong Yang, Lisa M Saksida, Timothy J Bussey   +2 more
exaly   +4 more sources