Results 21 to 30 of about 124,158 (160)

N-acetylgalactosamine positive perineuronal nets in the saccade-related-part of the cerebellar fastigial nucleus do not maintain saccade gain. [PDF]

open access: yesPLoS ONE, 2014
Perineuronal nets (PNNs) accumulate around neurons near the end of developmental critical periods. PNNs are structures of the extracellular matrix which surround synaptic contacts and contain chondroitin sulfate proteoglycans.
Adrienne Mueller   +3 more
doaj   +1 more source

EFFECTS OF AGE ON THE DENSITY OF PERINEURONAL NETS AND PARVALBUMIN-EXPRESSING INTERNEURONS IN THE RETROSPLENIAL CORTEX OF BEHAVIORALLY CHARACTERIZED MACAQUES

open access: yes, 2020
Aging takes a toll on all aspects of one’s body, including the brain. Deficits in cognitive function, which are associated with normal brain aging, have been seen in both human and macaque models.
Schwyhart, Rachel
core   +5 more sources

Environmental Enrichment From Birth Impacts Parvalbumin Expressing Cells and Wisteria Floribunda Agglutinin Labelled Peri-Neuronal Nets Within the Developing Murine Striatum

open access: yesFrontiers in Neuroanatomy, 2019
Environmental enrichment can dramatically affect both the development and function of neural circuits. This is accomplished, at least in part, by the regulation of inhibitory cellular networks and related extracellular matrix glycoprotein structures ...
Angela May O’Connor   +5 more
doaj   +1 more source

The Role of Perineuronal Nets in Learning and Memory [PDF]

open access: yes, 2018
The balance between stability and plasticity in the brain determines our ability to learn. A key molecular regulator of this balance includes perineuronal nets.
Nath, Moushumi
core   +1 more source

Otx2-PNN Interaction to Regulate Cortical Plasticity

open access: yesNeural Plasticity, 2016
The ability of the environment to shape cortical function is at its highest during critical periods of postnatal development. In the visual cortex, critical period onset is triggered by the maturation of parvalbumin inhibitory interneurons, which ...
Clémence Bernard, Alain Prochiantz
doaj   +1 more source

Calretinin as a marker for premotor neurons involved in upgaze in human brainstem

open access: yesFrontiers in Neuroanatomy, 2015
Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk   +6 more
doaj   +1 more source

Distribution and postnatal development of chondroitin sulfate proteoglycans in the perineuronal nets of cholinergic motoneurons innervating extraocular muscles

open access: yesScientific Reports, 2022
Fine control of extraocular muscle fibers derives from two subpopulations of cholinergic motoneurons in the oculomotor-, trochlear- and abducens nuclei.
Adrienn Ritok   +7 more
doaj   +1 more source

Cortical reorganization during adolescence: What the rat can tell us about the cellular basis

open access: yesDevelopmental Cognitive Neuroscience, 2020
The human cortex, particularly the prefrontal cortex, decreases in volume during adolescence which indicates considerable pruning. There is consistent evidence from human, monkey and rat tissue that synapses, dendritic spines and dendrites are pruned ...
Janice M. Juraska, Carly M. Drzewiecki
doaj   +1 more source

Neurogenesis mediated plasticity is associated with reduced neuronal activity in CA1 during context fear memory retrieval

open access: yesScientific Reports, 2022
Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans   +4 more
doaj   +1 more source

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