Results 31 to 40 of about 2,852 (175)
Frontiers in Neuroanatomy, 2019 Environmental enrichment can dramatically affect both the development and function of neural circuits. This is accomplished, at least in part, by the regulation of inhibitory cellular networks and related extracellular matrix glycoprotein structures ...
Angela May O’Connor +5 more
doaj +1 more source
Dynamics of perineuronal nets over amphibian metamorphosis
Journal of Comparative Neurology, 2020 Abstract Extracellular matrix materials known as perineuronal nets (PNNs) have been shown to have remarkable consequences for the maturation of neural circuits and stabilization of behavior. It has been proposed that, due to the possibly long‐lived biochemical nature of their components, PNNs may be an important substrate by which ...
Jacob A. Edwards +2 more
openaire +3 more sources
Perineuronal nets: Cruise from a honeycomb to the safety nets
Brain Research Bulletin, 2022 The extracellular matrix (ECM) is a significant component of the brain, constituting up to 20 % of the brain volume and perform multifarious functions during development, maturation and regeneration of the central nervous system (CNS). ECM molecules assemble systematically to form a relatively rigid and unique lattice-like structure, known as ...
Urmilla John, Nisha Patro, Ishan Patro
openaire +2 more sources
Scientific Reports, 2022 Fine control of extraocular muscle fibers derives from two subpopulations of cholinergic motoneurons in the oculomotor-, trochlear- and abducens nuclei.
Adrienn Ritok +7 more
doaj +1 more source
The extracellular matrix and perineuronal nets in memory
Molecular Psychiatry, 2022 AbstractAll components of the CNS are surrounded by a diffuse extracellular matrix (ECM) containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans (HSPGs), hyaluronan, various glycoproteins including tenascins and thrombospondin, and many other molecules that are secreted into the ECM and bind to ECM components. In addition,
Fawcett, James W +5 more
openaire +6 more sources
Calretinin as a marker for premotor neurons involved in upgaze in human brainstem
Frontiers in Neuroanatomy, 2015 Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk +6 more
doaj +1 more source
Cortical reorganization during adolescence: What the rat can tell us about the cellular basis
Developmental Cognitive Neuroscience, 2020 The human cortex, particularly the prefrontal cortex, decreases in volume during adolescence which indicates considerable pruning. There is consistent evidence from human, monkey and rat tissue that synapses, dendritic spines and dendrites are pruned ...
Janice M. Juraska, Carly M. Drzewiecki
doaj +1 more source
Scientific Reports, 2022 Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans +4 more
doaj +1 more source
Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions
Frontiers in Physiology, 2021 Perineuronal nets (PNNs) are widely present in the hypothalamus, and are thought to provide physical protection and ion buffering for neurons and regulate their synaptic plasticity and intracellular signaling.
Nan Zhang +21 more
doaj +1 more source
Proteoglycans in Perineuronal Nets.
ACTA HISTOCHEMICA ET CYTOCHEMICA, 1999 Proteoglycans are one of the major constituents of the extracellular matrix and cell membranes. In the brain, there are two major proteoglycans, chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. In the adult mammalian central nervous system, some species of chondroitin sulfate proteoglycan are localized in the ‘perineuronal net ...
Fumiko Matsui +2 more
openaire +2 more sources