Results 51 to 60 of about 124,158 (160)

Influence of enriched environment on viral encephalitis outcomes: behavioral and neuropathological changes in albino Swiss mice. [PDF]

PLoS ONE, 2011
An enriched environment has previously been described as enhancing natural killer cell activity of recognizing and killing virally infected cells. However, the effects of environmental enrichment on behavioral changes in relation to virus clearance and ...
Aline Andrade de Sousa, Renata Reis, João Bento-Torres, Nonata Trévia, Nara Alves de Almeida Lins, Aline Passos, Zaire Santos, José Antonio Picanço Diniz, Pedro Fernando da Costa Vasconcelos, Colm Cunningham, Victor Hugh Perry, Cristovam Wanderley Picanço Diniz   +11 more
doaj   +1 more source

Perineuronal nets--a specialized form of extracellular matrix in the adult nervous system.

, 1994
One century ago, Camillo Golgi described 'perineuronal nets' enwrapping the cell bodies and proximal dendrites of certain neurons in the adult mammalian central nervous system and suggested that they represent a supportive and protective scaffolding ...
Blümcke I, Celio MR
core   +1 more source

Perineuronal Nets in Neuropsychiatric Disorders

Brain Science Advances
Perineuronal nets (PNNs) are specialized extracellular matrix structures that enwrap select neuronal populations—particularly, parvalbumin-positive inhibitory interneurons.
Sonali Sikder, Ozlem Bozdagi Gunal
doaj   +1 more source

Subregion‐specific perineuronal net remodelling in the dorsal hippocampus drives vulnerability and resilience to chronic stress: The role of venlafaxine treatment

British Journal of Pharmacology, Volume 183, Issue 21, Page 6291-6305, November 2026.
Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio, Arianna Palumbo, Maria Teresa Gallo, Filippo Umberto Tancredi Veronesi, Giorgia Cortinovis, Piotr Gruca, Magdalena Lason, Ewa Litwa, Dominika Biala, Fabio Fumagalli, Mariusz Papp, Francesca Calabrese   +11 more
wiley   +1 more source

Quantitative microanalysis of perineuronal nets in brain tissue

, 2003
The relevance of the perineuronal nets (specialised extracellular matrix surrounding a part of the neurons in brain tissue) as a possible protection of neurons against oxidative stress induced by metal ions (e.g. Al, Fe, Cu and Zn) is an..
Butz, T., Morawski, M., Arendt, T., Reinert, T.   +3 more
core   +1 more source

Hyperacute Interleukin‐1β Production and Neutrophil Extracellular Trap Formation in the Cerebral Circulation of Stroke Patients with Large Vessel Occlusion

Annals of Neurology, Volume 100, Issue 4, Page 824-840, October 2026.
Acute ischemic stroke due to large vessel occlusion is associated with rapid intravascular immune activation. Analysis of arterial blood sampled distal to the thrombus during mechanical thrombectomy revealed increased extracellular adenosine triphosphate (ATP) and interleukin‐1β (IL‐1β) levels, evidence of inflammasome priming in monocytes, and ...
Justine Münsterberg, Caspar Brekenfeld, Hanna Englert, Marius Piepke, Regine J. Dress, Martin Oertel, Tina Fischer, Romy Hackbusch, Mingming Zha, Haodi Cai, Christian Casar, Ines S. Schädlich, Leo Winter, Alina Jander, Karoline Degenhardt, Maxim Bester, Fabian Flottmann, Uta Hanning, Brigitte Holst, Anna Worthman, Johanna Hiefner, Berenike Rutz, Eckhard Schlemm, Götz Thomalla, Bettina H. Clausen, Ann M. Stowe, Immo Prinz, Thiruma V. Arumugam, Markus Glatzel, Thomas Renné, Jens Fiehler, Eva Tolosa, Tim Magnus, Mathias Gelderblom   +33 more
wiley   +1 more source

Animals lacking link protein have attenuated perineuronal nets and persistent plasticity

, 2010
Chondroitin sulphate proteoglycans in the extracellular matrix restrict plasticity in the adult central nervous system and their digestion with chondroitinase reactivates plasticity.
Andrea Poli, T. T. Glant, M. R. Andrews, Kwok, Jessica C.F., J. W. Fawcett, Sathyaseelan S. Deepa, A. Poli, Fawcett, James W., Poli, Andrea, Forostyak, Serhiy, Carulli, Daniela, Melissa R. Andrews, James W. Fawcett, Daniela Carulli, Andrews, Melissa R., Tibor T. Glant, S. Forostyak, Andrews, Melissa Renee, Serhiy Forostyak, D. Carulli, Jessica C. F. Kwok, Elena Putignano, Glant, Tibor T., Kwok, Jessica C. F., J. C. Kwok, Tommaso Pizzorusso, E. Putignano, S. S. Deepa, Deepa, Sathyaseelan S., Putignano, Elena, Pizzorusso, Tommaso   +30 more
core   +1 more source

Caught in the Net: Perineuronal Nets and Addiction

Neural Plasticity, 2016
Exposure to drugs of abuse induces plasticity in the brain and creates persistent drug-related memories. These changes in plasticity and persistent drug memories are believed to produce aberrant motivation and reinforcement contributing to addiction ...
Megan Slaker, Jordan M. Blacktop, Barbara A. Sorg   +2 more
doaj   +1 more source

Perineuronal nets in HVC and plasticity in male canary song.

PLoS ONE, 2021
Songbirds learn their vocalizations during developmental sensitive periods of song memorization and sensorimotor learning. Some seasonal songbirds, called open-ended learners, recapitulate transitions from sensorimotor learning and song crystallization ...
Gilles Cornez, Shelley Valle, Ednei Barros Dos Santos, Ioana Chiver, Wendt Müller, Gregory F Ball, Charlotte A Cornil, Jacques Balthazart   +7 more
doaj   +1 more source

Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco, Danillo Alencar‐Coutinho, Ana Carolina Ferreira‐Scatone, Stella Diogo‐Cavassana, Jeanne Oiticica, Karina Lezirovitz, Ricardo Ferreira Bento   +6 more
wiley   +1 more source