Results 51 to 60 of about 134,149 (194)
Frontiers in Neuroanatomy, 2019 Environmental enrichment can dramatically affect both the development and function of neural circuits. This is accomplished, at least in part, by the regulation of inhibitory cellular networks and related extracellular matrix glycoprotein structures ...
Angela May O’Connor +5 more
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Otx2-PNN Interaction to Regulate Cortical Plasticity
Neural Plasticity, 2016 The ability of the environment to shape cortical function is at its highest during critical periods of postnatal development. In the visual cortex, critical period onset is triggered by the maturation of parvalbumin inhibitory interneurons, which ...
Clémence Bernard, Alain Prochiantz
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Calretinin as a marker for premotor neurons involved in upgaze in human brainstem
Frontiers in Neuroanatomy, 2015 Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk +6 more
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Scientific Reports, 2022 Fine control of extraocular muscle fibers derives from two subpopulations of cholinergic motoneurons in the oculomotor-, trochlear- and abducens nuclei.
Adrienn Ritok +7 more
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Cortical reorganization during adolescence: What the rat can tell us about the cellular basis
Developmental Cognitive Neuroscience, 2020 The human cortex, particularly the prefrontal cortex, decreases in volume during adolescence which indicates considerable pruning. There is consistent evidence from human, monkey and rat tissue that synapses, dendritic spines and dendrites are pruned ...
Janice M. Juraska, Carly M. Drzewiecki
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Scientific Reports, 2022 Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans +4 more
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Component-specific reduction in perineuronal nets in senescence-accelerated mouse strains
IBRO Neuroscience Reports, 2023 With increased life expectancy, age-related diseases are a significant health concern in Western societies. Animal models (e.g., rodents) have been used to understand age-related changes in brain function—particularly through the senescence-accelerated ...
Hiroshi Ueno +7 more
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Proteoglycans in Perineuronal Nets.
ACTA HISTOCHEMICA ET CYTOCHEMICA, 1999 Proteoglycans are one of the major constituents of the extracellular matrix and cell membranes. In the brain, there are two major proteoglycans, chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. In the adult mammalian central nervous system, some species of chondroitin sulfate proteoglycan are localized in the ‘perineuronal net ...
Matsui, Fumiko +2 more
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BiologyEvidence is strong that, in addition to fine motor control, there is an important role for the cerebellum in cognition and emotion. The deep nuclei of the mammalian cerebellum also contain the highest density of perineural nets—mesh-like structures that ...
Bernard G. Schreurs +2 more
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Expression of aggrecan components in perineuronal nets in the mouse cerebral cortex
IBRO Reports, 2018 Specific regions of the cerebral cortex are highly plastic in an organism’s lifetime. It is thought that perineuronal nets (PNNs) regulate plasticity, but labeling for Wisteria floribunda agglutinin (WFA), which is widely used to detect PNNs, is observed
Hiroshi Ueno +9 more
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