Results 71 to 80 of about 5,932 (219)

MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex [PDF]

open access: yes, 2015
Mutations in methyl-CpG-binding protein 2 (MeCP2) cause Rett syndrome, an autism spectrum-associated disorder with a host of neurological and sensory symptoms, but the pathogenic mechanisms remain elusive.
Cang, J.   +6 more
core   +1 more source

From Lobectomy to Completion Thyroidectomy: A Cohort Study and Systematic Review

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction The suggested management of thyroid cancer has been revised in the 2015 American Thyroid Association Management Guidelines, suggesting thyroid lobectomy alone for low‐risk thyroid cancer. However, precise patient selection is essential to identify who may need completion thyroidectomy (CT), avoiding the burden of a second surgery.
Idit Tessler   +7 more
wiley   +1 more source

Perineuronal nets in HVC and plasticity in male canary song.

open access: yesPLoS ONE, 2021
Songbirds learn their vocalizations during developmental sensitive periods of song memorization and sensorimotor learning. Some seasonal songbirds, called open-ended learners, recapitulate transitions from sensorimotor learning and song crystallization ...
Gilles Cornez   +7 more
doaj   +1 more source

Neuroanatomical Alterations in the CNTNAP2 Mouse Model of Autism Spectrum Disorder

open access: yesBrain Sciences, 2023
Autism spectrum disorder (ASD) is associated with neurodevelopmental alterations, including atypical forebrain cellular organization. Mutations in several ASD-related genes often result in cerebral cortical anomalies, such as the abnormal developmental ...
Tanya Gandhi   +4 more
doaj   +1 more source

Exploring the Production of Extracellular Matrix by Astrocytes in Response to Mimetic Traumatic Brain Injury [PDF]

open access: yes, 2016
Following injury to the central nervous system, extracellular modulations are apparent at the site of injury, often resulting in a glial scar. Astrocytes are mechanosensitive cells, which can create a neuroinhibitory extracellular environment in response
Walker, Addison
core   +2 more sources

A Periaxonal Net in the Zebrafish Central Nervous System [PDF]

open access: yes, 2003
We produced a monoclonal antibody, named A20, which specifically recognizes a 35 kDa protein and stains myelinated axons in zebrafish brain. The A20 antigen is located at the outside of the myelin layer of large axons, and comprises a fine meshwork ...
Alfei   +19 more
core   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Early Destruction of the Extracellular Matrix around Parvalbumin-Immunoreactive Interneurons in Creutzfeldt-Jakob Disease

open access: yesNeurobiology of Disease, 1999
GABA-interneurons immunoreactive (IR) for the calcium-binding protein parvalbumin are lost during the early stages of Creutzfeldt-Jakob disease (CJD) and diminution in their number may partially account for the neurological disturbances manifested in ...
Pavel V. Belichenko   +4 more
doaj   +1 more source

Inhibitory circuit dysfunction as a potential contributor to cortical reorganization in Glioblastoma progression

open access: yesNeurobiology of Disease
Glioblastoma (GBM) is a highly aggressive brain tumor that infiltrates surrounding brain tissue, profoundly affecting adjacent cortical areas. This study investigates how GBM reshapes the peritumoral cortex by examining plasticity changes in two GBM ...
Cristina Spalletti   +10 more
doaj   +1 more source

Extracellular matrix of the central nervous system: from neglect to challenge [PDF]

open access: yes, 2018
The basic concept, that specialized extracellular matrices rich in hyaluronan, chondroitin sulfate proteoglycans (aggrecan, versican, neurocan, brevican, phosphacan), link proteins and tenascins (Tn-R, Tn-C) can regulate cellular migration and axonal ...
Dours-Zimmermann, María   +1 more
core  

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