Results 71 to 80 of about 3,965 (209)
Influence of enriched environment on viral encephalitis outcomes: behavioral and neuropathological changes in albino Swiss mice. [PDF]
An enriched environment has previously been described as enhancing natural killer cell activity of recognizing and killing virally infected cells. However, the effects of environmental enrichment on behavioral changes in relation to virus clearance and ...
Aline Andrade de Sousa +11 more
doaj +1 more source
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source
Glioblastoma (GBM) is a highly aggressive brain tumor that infiltrates surrounding brain tissue, profoundly affecting adjacent cortical areas. This study investigates how GBM reshapes the peritumoral cortex by examining plasticity changes in two GBM ...
Cristina Spalletti +10 more
doaj +1 more source
Toxoplasma gondii infection damages the perineuronal nets in a murine model [PDF]
BACKGROUND Behavioral and neurochemical alterations associated with toxoplasmosis may be influenced by the persistence of tissue cysts and activation of an immune response in the brain of Toxoplasma gondii-infected hosts.
Ywlliane da Silva Rodrigues Meurer +8 more
doaj +2 more sources
Cilia in Nervous System Development, Function, and Disease
Cilia are evolutionarily conserved organelles that function as essential sensory and motility platforms in the nervous system. This review outlines key cilia‐dependent signaling pathways and their roles in neural development and function. Furthermore, it highlights how ciliary dysfunction can lead to a variety of neurological disorders, known as ...
Qingchao Li, Anqi Zhang, Ting Song
wiley +1 more source
Fragmented burst neuron perineuronal net immunostaining.
Parvalbumin-positive (PAV) putative burst neurons in the rostral interstitial nucleus of the medial longitudinal fasciculus (RIMLF) and in the paramedian pontine reticular formation (PPRF) were present in both the control and patient.
Wolfgang Härtig (232795) +6 more
core +1 more source
Normal abducens nucleus perineuronal net immunostaining.
Detection of perineuronal nets by aggrecan (ACAN) immunolabeling in the abducens nucleus (nVI) appeared similar in control subject and patient specimens.
Wolfgang Härtig (232795) +6 more
core +1 more source
AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets. [PDF]
Epilepsy is a serious brain disorder with diverse seizure types and epileptic syndromes. AMPA receptor antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzoquinoxaline-2,3-dione (NBQX) attenuates spontaneous recurrent seizures in rats.
Wen Chen +4 more
doaj +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Absent or fragmented omnipause neuron perineuronal net triple immunofluorescence staining.
Triple immunofluorescence staining for different components of perineuronal nets, revealed by a confocal laser scanning microscope. In the control case, omnipause neurons (OPN) are ensheathed by prominent perineuronal nets showing the same appearance ...
Wolfgang Härtig (232795) +6 more
core +1 more source

