Results 41 to 50 of about 5,812 (218)
Scientific Reports, 2022 Fine control of extraocular muscle fibers derives from two subpopulations of cholinergic motoneurons in the oculomotor-, trochlear- and abducens nuclei.
Adrienn Ritok +7 more
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The extracellular matrix and perineuronal nets in memory
Molecular Psychiatry, 2022 AbstractAll components of the CNS are surrounded by a diffuse extracellular matrix (ECM) containing chondroitin sulphate proteoglycans (CSPGs), heparan sulphate proteoglycans (HSPGs), hyaluronan, various glycoproteins including tenascins and thrombospondin, and many other molecules that are secreted into the ECM and bind to ECM components. In addition,
Fawcett, James W +5 more
openaire +6 more sources
Calretinin as a marker for premotor neurons involved in upgaze in human brainstem
Frontiers in Neuroanatomy, 2015 Eye movements are generated by different premotor pathways. Damage to them can cause specific deficits of eye movements, such as saccades. For correlative clinico-anatomical post-mortem studies of cases with eye movement disorders it is essential to ...
Christopher eAdamczyk +6 more
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Cortical reorganization during adolescence: What the rat can tell us about the cellular basis
Developmental Cognitive Neuroscience, 2020 The human cortex, particularly the prefrontal cortex, decreases in volume during adolescence which indicates considerable pruning. There is consistent evidence from human, monkey and rat tissue that synapses, dendritic spines and dendrites are pruned ...
Janice M. Juraska, Carly M. Drzewiecki
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Scientific Reports, 2022 Postnatal hippocampal neurogenesis has been demonstrated to affect learning and memory in numerous ways. Several studies have now demonstrated that increased neurogenesis can induce forgetting of memories acquired prior to the manipulation of ...
Alexandria Evans +4 more
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Hypothalamic Perineuronal Nets Are Regulated by Sex and Dietary Interventions
Frontiers in Physiology, 2021 Perineuronal nets (PNNs) are widely present in the hypothalamus, and are thought to provide physical protection and ion buffering for neurons and regulate their synaptic plasticity and intracellular signaling.
Nan Zhang +21 more
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Proteoglycans in Perineuronal Nets.
ACTA HISTOCHEMICA ET CYTOCHEMICA, 1999 Proteoglycans are one of the major constituents of the extracellular matrix and cell membranes. In the brain, there are two major proteoglycans, chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. In the adult mammalian central nervous system, some species of chondroitin sulfate proteoglycan are localized in the ‘perineuronal net ...
Fumiko Matsui +2 more
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Otx2-PNN Interaction to Regulate Cortical Plasticity
Neural Plasticity, 2016 The ability of the environment to shape cortical function is at its highest during critical periods of postnatal development. In the visual cortex, critical period onset is triggered by the maturation of parvalbumin inhibitory interneurons, which ...
Clémence Bernard, Alain Prochiantz
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Component-specific reduction in perineuronal nets in senescence-accelerated mouse strains
IBRO Neuroscience Reports, 2023 With increased life expectancy, age-related diseases are a significant health concern in Western societies. Animal models (e.g., rodents) have been used to understand age-related changes in brain function—particularly through the senescence-accelerated ...
Hiroshi Ueno +7 more
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Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin. [PDF]
, 2014 The in situ hybridization Allen Mouse Brain Atlas was mined for proteases expressed in the somatosensory cerebral cortex. Among the 480 genes coding for protease/peptidases, only four were found enriched in cortical interneurons: Reln coding for reelin ...
A Bernard +43 more
core +2 more sources