Results 81 to 90 of about 2,852 (175)

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, Volume 604, Issue 4, Page 1531-1546, 15 February 2026.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

Frontiers in Physiology, 2019
Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder ...
Helen B. Stolp, Helen B. Stolp, Bobbi Fleiss, Bobbi Fleiss, Bobbi Fleiss, Yoko Arai, Veena Supramaniam, Regina Vontell, Regina Vontell, Sebastian Birtles, Abi G. Yates, Abi G. Yates, Ana A. Baburamani, Claire Thornton, Claire Thornton, Mary Rutherford, A. David Edwards, Pierre Gressens, Pierre Gressens   +18 more
doaj   +1 more source

Alpha-pinene and dizocilpine (MK-801) attenuate kindling development and astrocytosis in an experimental mouse model of epilepsy

IBRO Reports, 2020
Understanding the molecular and cellular mechanisms involved during the onset of epilepsy is crucial for elucidating the overall mechanism of epileptogenesis and therapeutic strategies.
Hiroshi Ueno, Atsumi Shimada, Shunsuke Suemitsu, Shinji Murakami, Naoya Kitamura, Kenta Wani, Yu Takahashi, Yosuke Matsumoto, Motoi Okamoto, Takeshi Ishihara   +9 more
doaj   +1 more source

Anti‐Neuroinflammation Activity of Essential Oils and Fatty Acids

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Neuroinflammation plays a pivotal role in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD) and Parkinson's disease (PD). Current pharmacological interventions, such as NSAIDs and corticosteroids, are limited by systemic toxicity and insufficient efficacy in targeting chronic neuroinflammatory processes.
Zelong Jin, Yige Song, Ahmed Attia Ahmed Abdelmoaty, Feng Lin, Jiujun Li, Xianyang Chen   +5 more
wiley   +1 more source

The role of brevican regulation in the antidepressant effects of electroacupuncture in a chronic stress rat model

Journal of Traditional Chinese Medical Sciences
Objective: To investigate the mechanism of electroacupuncture (EA) for treating depression and to explore the role of brevican in the medial prefrontal cortex (mPFC) in modulating stress susceptibility and the antidepressant effects of EA in rats ...
Cong Gai, Zhenyu Guo, Kai Guo, Shixin Yang, Yi Zhang, Huimin Zhu, Feifei Kan, Hongmei Sun, Die Hu   +8 more
doaj   +1 more source

Saccadic Palsy following Cardiac Surgery: Possible Role of Perineuronal Nets.

PLoS ONE, 2015
ObjectivePerineuronal nets (PN) form a specialized extracellular matrix around certain highly active neurons within the central nervous system and may help to stabilize synaptic contacts, promote local ion homeostasis, or play a protective role.
Scott D Z Eggers, Anja K E Horn, Sigrun Roeber, Wolfgang Härtig, Govind Nair, Daniel S Reich, R John Leigh   +6 more
doaj   +1 more source

Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix

Frontiers in Cellular Neuroscience, 2018
The neural extracellular matrix (ECM) is enriched with hyaluronic acid, chondroitin sulfate proteoglycans (CSPGs) and the glycoprotein tenascin-R, which play important roles in synaptic plasticity, as shown by studies of the CA1 region of the hippocampus.
Hussam Hayani, Inseon Song, Alexander Dityatev, Alexander Dityatev, Alexander Dityatev   +4 more
doaj   +1 more source

Restoring vision in adult amblyopia by enhancing plasticity through deletion of the transcriptional repressor REST

iScience
Summary: Visual cortical plasticity is high during early life, but gradually decreases with development. This is due to the Otx2-driven maturation of intracortical inhibition that parallels the condensation of extracellular matrix components into ...
Dmytro Shmal, Giulia Mantero, Thomas Floss, Fabio Benfenati, José Fernando Maya-Vetencourt   +4 more
doaj   +1 more source

Perineuronal nets in neurodegeneration

Oncotarget, 2016
Lemarchant, Sighild, Wojciechowski, Sara, Koistinaho, Jari   +2 more
openaire   +2 more sources

Perineuronal Net Microscopy: From Brain Pathology to Artificial Intelligence

International Journal of Molecular Sciences
Perineuronal nets (PNN) are a special highly structured type of extracellular matrix encapsulating synapses on large populations of CNS neurons. PNN undergo structural changes in schizophrenia, epilepsy, Alzheimer’s disease, stroke, post-traumatic conditions, and some other brain disorders.
Mikhail Paveliev, Anton A. Egorchev, Foat Musin, Nikita Lipachev, Anastasiia Melnikova, Rustem M. Gimadutdinov, Aidar R. Kashipov, Dmitry Molotkov, Dmitry E. Chickrin, Albert V. Aganov   +9 more
openaire   +2 more sources