Results 31 to 40 of about 85,043 (305)

Hsp40 overexpression in pacemaker neurons delays circadian dysfunction in a Drosophila model of Huntington's disease

open access: yesDisease Models & Mechanisms, 2022
Circadian disturbances are early features of neurodegenerative diseases, including Huntington's disease (HD). Emerging evidence suggests that circadian decline feeds into neurodegenerative symptoms, exacerbating them.
Pavitra Prakash   +2 more
doaj   +1 more source

Circadian rhythms and post-transcriptional regulation in higher plants [PDF]

open access: yes, 2015
The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Romanowski, Andrés   +1 more
core   +3 more sources

Circadian rhythmicity by autocatalysis. [PDF]

open access: yesPLoS Computational Biology, 2006
The temperature compensated in vitro oscillation of cyanobacterial KaiC phosphorylation, the first example of a thermodynamically closed system showing circadian rhythmicity, only involves the three Kai proteins (KaiA, KaiB, and KaiC) and ATP.
Arun Mehra   +5 more
doaj   +1 more source

Circadian clock genes Bmal1 and Period may regulate nocturnal spawning by controlling sex hormone secretion in razor clam Sinonovacula constricta

open access: yesFrontiers in Marine Science, 2022
The circadian clock is an endogenous regulation mechanism that coordinates biological processes with daily changes, which are regulated by circadian clock genes.
Yanzi Liu   +7 more
doaj   +1 more source

Orchestrated transcription of biological processes in the marine picoeukaryote Ostreococcus exposed to light/dark cycles [PDF]

open access: yes, 2010
Background: Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species of Ostreococcus and Micromonas has led to the emergence of picophytoplankton comparative ...
Bouget, François-Yves   +7 more
core   +7 more sources

Nuclear Envelope Protein MAN1 Regulates the Drosophila Circadian Clock via Period

open access: yesNeuroscience Bulletin, 2019
Almost all organisms exhibit ~24-h rhythms, or circadian rhythms, in a plentitude of biological processes. These rhythms are driven by endogenous molecular clocks consisting of a series of transcriptional and translational feedback loops. Previously, we have shown that the inner nuclear membrane protein MAN1 regulates this clock and thus the locomotor ...
Bei, Bu   +3 more
openaire   +3 more sources

Codon usage affects the structure and function of the Drosophila circadian clock protein PERIOD [PDF]

open access: yesGenes & Development, 2016
Codon usage bias is a universal feature of all genomes, but its in vivo biological functions in animal systems are not clear. To investigate the in vivo role of codon usage in animals, we took advantage of the sensitivity and robustness of the Drosophila circadian system.
Fu, Jingjing   +7 more
openaire   +4 more sources

Myb‐like transcription factors have epistatic effects on circadian clock function but additive effects on plant growth

open access: yesPlant Direct, 2023
The functions of closely related Myb‐like repressor and Myb‐like activator proteins within the plant circadian oscillator have been well‐studied as separate groups, but the genetic interactions between them are less clear.
Cassandra L. Hughes, Stacey L. Harmer
doaj   +1 more source

Analysis of DNA-Damage Response to ionizing radiation in serum-shock synchronized human fibroblasts. [PDF]

open access: yes, 2017
Many aspects of cellular physiology, including cellular response to genotoxic stress, are related to the circadian rhythmicity induced by the molecular clock.
Barbieri, Vito   +4 more
core   +1 more source

Solving the mystery of human sleep schedules one mutation at a time. [PDF]

open access: yes, 2013
Sleep behavior remains one of the most enigmatic areas of life. The unanswered questions range from "why do we sleep?" to "how we can improve sleep in today's society?" Identification of mutations responsible for altered circadian regulation of human ...
Fu, Ying-Hui   +2 more
core   +1 more source

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