Results 1 to 10 of about 12,081 (284)

Periodontal tissue stem cells and mesenchymal stem cells in the periodontal ligament

Japanese Dental Science Review, 2022
Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of periodontal tissues, are found in the periodontal ligament (PDL).
Tomoaki Iwayama, Hiromi Sakashita, Masahide Takedachi, Shinya Murakami   +3 more
doaj   +3 more sources

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine     [PDF]

Stem Cells, 2010
AbstractPeriodontitis is one of the most widespread infectious diseases in humans. It is the main cause of tooth loss and associated with a number of systemic diseases. Until now, there is no appropriate method for functional periodontal tissue regeneration. Here, we establish a novel approach of using allogeneic periodontal ligament stem cells (PDLSCs)
Gang Ding, Yi Liu, Wei Wang, Fulan Wei, Dayong Liu, Zhipeng Fan, Yunqing An, Chunmei Zhang, Songlin Wang   +8 more
openalex   +4 more sources

Pyroptosis of periodontal ligament stem cells aggravates periodontitis via Piezo1 channel. [PDF]

iScience
Periodontitis is a chronic inflammatory disease that leads to periodontal tissue destruction, but the mechanisms underlying inflammation-induced stem cell dysfunction remain unclear. This study examines the role of Piezo1 in modulating pyroptosis in periodontal ligament stem cells (PDLSCs) during periodontitis.
Chen P, Liu D, Zhou YK, Jiang JH, Yang RL.   +4 more
europepmc   +3 more sources

The effect of the Wnt pathway on the osteogenic differentiation of periodontal ligament stem cells in different environments [PDF]

PeerJ
Alveolar bone defects have always been an urgent problem in the oral cavity. For some patients with periodontal disease or undergoing orthodontic treatment or implant restoration, alveolar bone defects can greatly inconvenience clinical diagnosis and ...
Qi Su, Fengqiong Huang, XiuLei Fang, Qiang Lin   +3 more
doaj   +3 more sources

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis [PDF]

Frontiers in Cell and Developmental Biology, 2021
Periodontitis is an immune inflammatory disease that leads to progressive destruction of bone and connective tissue, accompanied by the dysfunction and even loss of periodontal ligament stem cells (PDLSCs). Pyroptosis mediated by gasdermin-D (GSDMD) participates in the pathogenesis of inflammatory diseases.
Qin Chen, Xingguang Liu, Dingyu Wang, Jisi Zheng, Lu Chen, Qianyang Xie, Xiaohan Liu, Sujuan Niu, Guanlin Qu, Jianfeng Lan, Jing Li, Chi Yang, Duohong Zou   +12 more
openaire   +3 more sources

The Experimental Study of Periodontal Ligament Stem Cells Derived Exosomes with Hydrogel Accelerating Bone Regeneration on Alveolar Bone Defect

Pharmaceutics, 2022
Introduction: this study was conducted to investigate the osteogenic ability of periodontal ligament stem cells (PDLSCs) derived exosomes (PDLSCs-Exos) and the effect of PDLSCs-Exos with hydrogel on alveolar bone defect repairment in the rat.
Yang Zhao, Yujia Gong, Xianbo Liu, Jia He, Bowen Zheng, Yi Liu   +5 more
doaj   +1 more source

Research progress on the regulatory mechanism of estrogen in periodontal ligament cells repair and the reconstruction of periodontal tissue

口腔疾病防治, 2021
Periodontium regeneration and repair is a controversial and difficult point in the treatment of periodontosis. The proliferation, differentiation, migration and adhesion of periodontal ligament cells and the dynamic relationship between periodontal ...
LI Qi, WANG He, HUANG Zijun, HAN Qianqian   +3 more
doaj   +1 more source

The Ability of Mesenchymal Stem Cells for Periodontal Tissue Regeneration: A Comprehensive Review of Literature

مجله دانشکده دندانپزشکی اصفهان, 2022
Stem cells and tissue engineering have shown great potential in the treatment of periodontal diseases since their introduction.
MohammadMostafa Aghamohseni, Shirin Zahra Farhad   +1 more
doaj   +1 more source

Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

Stem Cells International, 2022
Background. Angiogenic tissue engineering is a vital problem waiting to be settled for periodontal regeneration. Erythropoietin, a multieffect cytokine, has been reported as a protective factor for cell fate.
Denghao Huang, Jie Lei, Xingrui Li, Zhonghao Jiang, Maoxuan Luo, Yao Xiao   +5 more
doaj   +1 more source

Therapeutic potential of periodontal ligament stem cells

World Journal of Stem Cells, 2021
Inflammatory periodontal disease known as periodontitis is one of the most common conditions that affect human teeth and often leads to tooth loss. Due to the complexity of the periodontium, which is composed of several tissues, its regeneration and subsequent return to a homeostatic state is challenging with the therapies currently available. Cellular
Queiroz, Aline, Albuquerque-Souza, Emmanuel, Gasparoni, Leticia Miquelitto, de França, Bruno Nunes, Pelissari, Cibele, Trierveiler, Marília, Holzhausen, Marinella   +6 more
openaire   +2 more sources