Results 11 to 20 of about 821,529 (204)

Cancer-associated adipocytes promote peritoneal metastasis of colorectal signet ring cell carcinoma via FABP4 induction [PDF]

open access: yesCell Communication and Signaling
Background Colorectal signet ring cell carcinoma (SRCC) is a rare and aggressive subtype with a high propensity for peritoneal metastasis, yet the underlying mechanisms remain poorly understood.
Weixing Dai   +7 more
doaj   +2 more sources

Blood ctDNA-specific markers predict the risk of peritoneal metastasis for advanced gastric cancer [PDF]

open access: yesDiscover Oncology
Objective The aim of this study was to investigate the value of early postoperative ctDNA dynamic monitoring (TP53/KRAS/PIK3CA gene mutations) combined with clinicopathologic factors in risk stratification of postoperative peritoneal metastasis in ...
FangZhou Xing   +5 more
doaj   +2 more sources

Small peritoneal macrophages are accelerators of peritoneal metastasis of colorectal cancer. [PDF]

open access: yesTransl Cancer Res
The peritoneal cavity (PerC) constitutes a distinct anatomical compartment that harbors various subpopulations of peritoneal macrophages. However, there remains a significant gap in our understanding of the functions of these macrophage subpopulations in the context of peritoneal metastasis of colorectal cancer (PM-CRC) and their roles in the tumor ...
Yang W   +6 more
europepmc   +3 more sources

Factors Affecting Positive Peritoneal Lavage Cytology in Patients with Stage II and III Colorectal Cancer with R0 Resection: A Multi-institutional, Prospective Study

open access: yesJournal of the Anus, Rectum and Colon, 2021
Objectives: This study aimed to explore the risk factors associated with cancer cell exfoliation in Stage II and III colorectal cancer (CRC). Methods: This multicenter, prospective, observational study targeted 1,698 patients with cStage II and III CRC ...
Harunobu Sato   +5 more
doaj   +1 more source

Progress in application of peritoneal lavage fluid circulating tumor DNA to predicting peritoneal metastasis of gastrointestinal cancer

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Peritoneal metastasis is one of the important causes of death in patients with gastrointestinal cancer and is also a difficult point in clinical diagnosis and treatment.
BAI Long   +3 more
doaj   +1 more source

Advance of peritoneal metastasis of colorectal cancer

open access: yes结直肠肛门外科, 2023
Peritoneal metastasis is a common distant metastasis of colorectal cancer and it is associated with poor prognosis. While previously peritoneal metastasis of colorectal cancer is considered a terminal stage of the disease.
Zhou Shiqi, Zhu Yuping
doaj   +1 more source

Single-cell sequencing of ascites fluid illustrates heterogeneity and therapy-induced evolution during gastric cancer peritoneal metastasis

open access: yesNature Communications, 2023
Peritoneal metastasis is one of the most common forms of death for gastrointestinal cancers, however, its cell composition is incompletely understood. Here, the authors use single cell RNA-seq of peritoneal metastases from 35 patients and show diversity ...
Xuan-Zhang Huang   +16 more
semanticscholar   +1 more source

MiR-216b inhibits gastric cancer proliferation and migration by targeting PARK7

open access: yesIndian Journal of Pathology and Microbiology, 2021
Objective: Postoperative recurrence and metastasis of gastric cancer is still a difficult problem in medical field. About 60% of patients with advanced gastric cancer die from peritoneal metastasis, which has become one of the main causes of death of ...
Guo-Min Zhu   +5 more
doaj   +1 more source

Omental cancer‐associated fibroblast‐derived exosomes with low microRNA‐29c‐3p promote ovarian cancer peritoneal metastasis

open access: yesCancer Science, 2023
Ovarian cancer (OC) is characterized by frequent widespread peritoneal metastasis. Cancer‐associated fibroblasts (CAFs) represent a critical stromal component of metastatic niche and promote omentum metastasis in OC patients.
Qing Han   +10 more
semanticscholar   +1 more source

Comprehensive analysis of m6A-modified circRNAs in peritoneal metastasis of high grade serious carcinoma of ovary

open access: yesFrontiers in Oncology, 2022
PurposeHigh-grade serous ovarian cancer (HGSOC) remains the most lethal female cancer due to metastasis. CircRNAs are recently identified to be modified by N6-methyladenosine (m6A) in many cells.
Lin Guo   +5 more
doaj   +1 more source

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