Results 41 to 50 of about 821,529 (204)

Obesity promotes gastric cancer metastasis via diacylglycerol acyltransferase 2-dependent lipid droplets accumulation and redox homeostasis

open access: yesRedox Biology, 2020
Experimental and molecular epidemiological studies indicate important roles for adipose tissue or high-fat diet (HFD) in tumor growth and metastasis. Gastric cancer (GC) possesses a metastatic predilection for the adipocyte-rich peritoneum.
Shuai Li   +11 more
doaj   +1 more source

A PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis

open access: yesSignal Transduction and Targeted Therapy, 2022
Pleural and peritoneal metastasis accompanied by malignant pleural effusion (MPE) or malignant ascites (MA) is frequent in patients with advanced solid tumors that originate from the lung, breast, gastrointestinal tract and ovary.
Qizhi Ma   +25 more
semanticscholar   +1 more source

EIF4E regulates STEAP1 expression in peritoneal metastasis [PDF]

open access: yesJournal of Cancer, 2020
Gastric cancer is the most prominent form of malignancy in China, and the high mortality associated with it is mostly due to peritoneal metastasis. We have previously elucidated that the RNA-binding protein poly r(C) binding protein 1 (PCBP1) and miR-3978 function as repressors of peritoneal metastasis, partially by downregulation of six-transmembrane ...
Jiang, Jun-nan   +3 more
openaire   +2 more sources

Hypoxia-Induced CD36 Expression in Gastric Cancer Cells Promotes Peritoneal Metastasis via Fatty Acid Uptake

open access: yesAnnals of Surgical Oncology, 2022
Background The lipid scavenger receptor cluster of differentiation 36 (CD36) has been shown to have a pro-metastatic function in several cancers. Adipose tissue, a favorable site for peritoneal metastasis (PM) from gastric cancer (GC), promotes this ...
Tatsuya Aoki   +12 more
semanticscholar   +1 more source

Animal models of colorectal peritoneal metastasis

open access: yesPleura and Peritoneum, 2016
AbstractColorectal cancer remains an important cause of mortality worldwide. The presence of peritoneal carcinomatosis (PC) causes significant symptoms and is notoriously difficult to treat. Therefore, informative preclinical research into the mechanisms and possible novel treatment options of colorectal PC is essential in order to improve the ...
Félix, Gremonprez   +2 more
openaire   +2 more sources

Gastric Cancer With Peritoneal Metastasis—A Comprehensive Review of Current Intraperitoneal Treatment Modalities

open access: yesFrontiers in Oncology, 2022
The treatment of patients with peritoneal metastasis from gastric cancer continues to evolve. With various forms of intraperitoneal drug delivery available, it is now possible to reach the sites of peritoneal metastases, which were otherwise sub ...
A. Prabhu   +3 more
semanticscholar   +1 more source

New views on pathogenesis and diagnosis of peritoneal carcinomatosis

open access: yesКреативная хирургия и онкология, 2023
Peritoneal metastasis occurs in a number of heterogeneous tumors originating from the ovaries, stomach, intestines, pancreas, lungs, breast, and melanoma. Peritoneal carcinomatosis significantly reduces overall survival.
K. R. Ishmuratova, K. Sh. Gantsev
doaj   +1 more source

Site of Recurrence and Survival after Surgery for Colorectal Peritoneal Metastasis.

open access: yesJournal of the National Cancer Institute, 2021
BACKGROUND Multimodal treatment, including systemic treatment and surgery, improved the prognosis of peritoneal metastasis (PM). Despite all efforts, recurrence rates remain high, and only little data is available about clinical behavior or molecular ...
E. Breuer   +16 more
semanticscholar   +1 more source

Peritoneal and gastric metastasis from invasive lobular breast carcinoma: a case report [PDF]

open access: yesKosin Medical Journal, 2015
Peritoneal and gastrointestinal metastasis from breast cancer is very rare. We report here a rare case of metastatic peritoneal and gastric cancer from breast lobular carcinoma after modified radical mastectomy.
Yoon Seok Kim   +3 more
doaj   +1 more source

Spheroid Formation and Peritoneal Metastasis in Ovarian Cancer: The Role of Stromal and Immune Components

open access: yesInternational Journal of Molecular Sciences, 2022
Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) accompanied by ascites formation is the most unfavorable factor in the progression ...
M. Rakina   +4 more
semanticscholar   +1 more source

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