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PERMEATION ENHANCERS

2022
Authors : Prof.
Prof. ANUPAMA DIWAN, SHEKHAR SHARMA
openaire   +1 more source

Effect of Iontophoresis and Permeation Enhancers on the Permeation of an Acyclovir Gel

Current Drug Delivery, 2010
The purpose of the present study was to explore the combined effect of chemical enhancers and iontophoresis on the in vitro permeation of acyclovir gel across porcine skin. Acyclovir gel was formulated using carbopol 940 and hydroxypropyl methylcellulose K4M (HPMC K4M). Effect of drug concentration on the delivery of acyclovir was examined.
Subhash S, Vaghani   +6 more
openaire   +2 more sources

Photothermal-Assisted Hydrogen Permeation Enhancement

Sensors and Actuators B: Chemical, 2022
Herein, we propose and demonstrate a novel all-optical photothermal-assisted hydrogen permeation enhancement scheme by using a special optics-mechanics synergistic fiber optic hydrogen sensor. This design of the scheme is mainly based on the interdependencies between Pd-hydrogen reaction temperature and hydrogen permeation; as to observe the influence ...
Xinpu Zhang   +5 more
openaire   +1 more source

Effects of Adhesives and Permeation Enhancers on the Skin Permeation of Captopril

Drug Development and Industrial Pharmacy, 2001
To formulate a transdermal drug delivery system of captopril, monolithic adhesive matrix type patches containing 20% captopril, different pressure-sensitive adhesives, and various permeation enhancers were prepared using a labcoater. The effects of the adhesives and permeation enhancers on skin permeation of captopril from the prepared patches were ...
E S, Park   +3 more
openaire   +2 more sources

Homoharringtonine is a transdermal granular permeation enhancer

Biochemical and Biophysical Research Communications, 2022
Although modulation of claudin-1-based tight junction (TJ) in stratum granulosum is an option for transdermal absorption of drugs, granular permeation enhancers have never been developed. We previously found that homoharringtonine (HHT), a natural alkanoid, weakened intestinal epithelial barrier with changing expression and cellular localization of TJ ...
Akihiro, Watari   +6 more
openaire   +2 more sources

Transbuccal Permeation of a Nucleoside Analog, Dideoxycytidine: Effects of Menthol as a Permeation Enhancer

International Journal of Pharmaceutics, 1999
The use of a safe and effective permeation enhancer is paramount to the success of a buccal drug delivery system intended for systemic drug absorption. The enhancing effects of menthol (dissolved in an aqueous buffer in the absence of co-enhancers) on buccal permeation of a model hydrophilic nucleoside analog, dideoxycytidine (ddC), were investigated ...
Mansoor Khan
exaly   +3 more sources

Intestinal Permeation Enhancers

Journal of Pharmaceutical Sciences, 2000
This review addresses the field of improving oral bioavailability through the use of excipients that increase intestinal membrane permeability. The critical issues to consider in evaluating these approaches are 1) the extent of bioavailability enhancement achieved, 2) the influence of formulation and physiological variables, 3) toxicity associated with
openaire   +2 more sources

Permeation Enhancers for Transdermal Drug Delivery

Drug Development and Industrial Pharmacy, 2000
The transdermal route has been recognized as one of the highly potential routes of systemic drug delivery and provides the advantage of avoidance of the first-pass effect, ease of use and withdrawal (in case of side effects), and better patient compliance.
V R Sinha
exaly   +3 more sources

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