Results 161 to 170 of about 77,745 (214)

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

Advanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang, Meng‐Hao Li, Liang Cheng, Tian‐Shou Zhang, Hui Hui, Yan Wang, Hong‐Pu Zhang, Bo‐Wen Liu, Lin Wang, Ying‐Wei Yang   +9 more
wiley   +1 more source

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

[The role of peroxide oxidation of lipids in the etiopathogenesis of atherosclerosis].

Vojnosanitetski pregled, 1991
P, Jović, M, Simović
openaire   +1 more source

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An Oxidatively Releasable Caging Group that Senses Lipid Peroxidation.

ChemInform, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Kari A, Trumbull, Bruce P, Branchaud
openaire   +2 more sources

Lipid peroxidation in the presence of iron oxides

Toxicological & Environmental Chemistry, 2000
Exposure to iron oxides dusts may lead to lung cancers among exposed population. To evaluate the involvement of iron‐containing particles in lipid peroxidation by production of reactive oxygen species, hematite, magnetite (iron oxides), and crocidolite (asbestos compound) were tested.
Salem Chouchane, Joëlle Guignard, Jeanine Fournier   +2 more
openaire   +1 more source

Promotion of Lipid Oxidation by Selenate and Selenite and Indicators of Lipid Peroxidation in the Rat

Biological Trace Element Research, 2001
The AIN-93 reformulation of the AIN-76A rodent diet includes a change in selenium supplement from sodium selenite to sodium selenate to reduce dietary lipid peroxidation. A change to selenate as the standard form of Se in rat diets would render results from previous work using selenite less relevant for comparison with studies using the AIN-93 ...
M A, Moak, M J, Christensen
openaire   +2 more sources

Effect of Inhibition of Lipid Peroxidation on Myocardial Oxidant Damage

Journal of Surgical Research, 1994
Oxygen-derived free radical-mediated injury occurs frequently following prolonged ischemia and reperfusion. Recently, the nonglucocorticoid steroid U74006F has been shown to exert therapeutic effects presumably secondary to its peroxide inhibitory effect.
Y H, Salem, S A, Dulchavsky, S, Dutta, L N, Diebel   +3 more
openaire   +2 more sources

Lipid peroxidation products as oxidative stress biomarkers

BioFactors, 2008
AbstractOxidative stress induced by reactive oxygen and nitrogen species has been implicated in the pathogenesis of various disorders and diseases. Biomarkers are needed for assessment of oxidative stress status in vivo and also for health examination, diagnosis at early stage, prognosis, safe and efficient drug development, and evaluation of efficacy ...
openaire   +2 more sources

Protein thiol oxidation and lipid peroxidation in patients with uraemia

Scandinavian Journal of Clinical and Laboratory Investigation, 2004
Patients with uraemia are exposed to increased oxidative stress. In this study, a series of oxidative stress markers were measured in patients with chronic renal failure (CRF) and patients with CRF on haemodialysis (HD) compared to normal controls to establish whether there is enhanced oxidative stress on HD therapy in uraemic subjects.Protein thiol ...
M, Prakash, S, Upadhya, R, Prabhu
openaire   +2 more sources