Results 61 to 70 of about 33,744 (220)

Multiple genes contribute to anhydrobiosis (tolerance to extreme desiccation) in the nematode Panagrolaimus superbus

Genetics and Molecular Biology, 2017
The molecular basis of anhydrobiosis, the state of suspended animation entered by some species during extreme desiccation, is still poorly understood despite a number of transcriptome and proteome studies.
Cláudia Carolina Silva Evangelista, Giovanna Vieira Guidelli, Gustavo Borges, Thais Fenz Araujo, Tiago Alves Jorge de Souza, Ubiraci Pereira da Costa Neves, Alan Tunnacliffe, Tiago Campos Pereira   +7 more
doaj   +1 more source

Function and Regulation of Chloroplast Peroxiredoxin IIE

Antioxidants, 2021
Peroxiredoxins (PRX) are thiol peroxidases that are highly conserved throughout all biological kingdoms. Increasing evidence suggests that their high reactivity toward peroxides has a function not only in antioxidant defense but in particular in redox ...
Anna Dreyer, Patrick Treffon, Daniel Basiry, Anna Maria Jozefowicz, Andrea Matros, Hans-Peter Mock, Karl-Josef Dietz   +6 more
doaj   +1 more source

Glutaredoxine reduzieren schnell Glutathionhydroper‐ und Glutathionpolysulfide

Angewandte Chemie, EarlyView.
Glutaredoxine (Grx) reduzieren Glutathionpolysulfide (GSSnSG) schnell zu Glutathionhydroper/polysulfiden (GSSnH) oder GSSnH zu Wasserstoff(poly)sulfiden (H2Sn). Die Reduktion glutathionylierter Grx durch reduziertes Glutathion (GSH) liefert Glutathiondisulfid (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Peroxiredoxin Catalysis at Atomic Resolution [PDF]

Structure, 2016
Peroxiredoxins (Prxs) are ubiquitous cysteine-based peroxidases that guard cells against oxidative damage, are virulence factors for pathogens, and are involved in eukaryotic redox regulatory pathways. We have analyzed catalytically active crystals to capture atomic resolution snapshots of a PrxQ subfamily enzyme (from Xanthomonas campestris ...
Perkins, Arden, Parsonage, Derek, Nelson, Kimberly J., Ogba, O. Maduka, Cheong, Paul Ha-Yeon, Poole, Leslie B., Karplus, P. Andrew   +6 more
openaire   +3 more sources

Microorganisms: A Potential Source of Bioactive Molecules for Antioxidant Applications

Molecules, 2021
Oxidative stress originates from an elevated intracellular level of free oxygen radicals that cause lipid peroxidation, protein denaturation, DNA hydroxylation, and apoptosis, ultimately impairing cell viability.
Alka Rani, Khem Chand Saini, Felix Bast, Sanjeet Mehariya, Shashi Kant Bhatia, Roberto Lavecchia, Antonio Zuorro   +6 more
doaj   +1 more source

Glutaredoxins Rapidly Reduce Glutathione Hydroper‐ and Polysulfides

Angewandte Chemie International Edition, EarlyView.
Glutaredoxins (Grx) rapidly reduce glutathione polysulfides (GSSnSG) to glutathione hydroper/polysulfides (GSSnH) or GSSnH to hydrogen (poly)sulfides (H2Sn). Reduction of glutathionylated glutaredoxins by reduced glutathione (GSH) yields glutathione disulfide (GSSG).
Philipp Reinert, Seiryo Ogata, Laura Leiskau, Sernur Sena Yildiz, Takaaki Akaike, Uladzimir Barayeu, Marcel Deponte   +6 more
wiley   +1 more source

Discovery of Spilanthol Endoperoxide as a Redox Natural Compound Active against Mammalian Prx3 and Chlamydia trachomatis Infection

Antioxidants, 2020
Chlamydia trachomatis (Ct) is a bacterial intracellular pathogen responsible for a plethora of diseases ranging from blindness to pelvic inflammatory diseases and cervical cancer.
Rosine Dushime, Yunhuang Zhu, Hanzhi Wu, Daniel Saez, Kirtikar Shukla, Heather Brown-Harding, Maique W. Biavatti, Kimberly J. Nelson, Leslie B. Poole, William T. Lowther, Paul B. Jones, Cristina M. Furdui, Allen W. Tsang   +12 more
doaj   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

The Role of Peroxiredoxins in Cancer Development

Biology, 2023
Peroxiredoxins (Prxs) are antioxidant enzymes with ubiquitous expression in human tissues. Prxs are expressed in archaea, bacteria, and eukaryota, often in multiple isoforms. Because of their abundant expression in different cellular organelles and extraordinary sensitivity to H2O2, Prxs are among the first defenses against oxidative stress.
Pratik Thapa, Hong Jiang, Na Ding, Yanning Hao, Aziza Alshahrani, Qiou Wei   +5 more
openaire   +3 more sources

First Report of a Peroxiredoxin Homologue in Jellyfish: Molecular Cloning, Expression and Functional Characterization of CcPrx4 from Cyanea capillata

Marine Drugs, 2014
We first identified and characterized a novel peroxiredoxin (Prx), designated as CcPrx4, from the cDNA library of the tentacle of the jellyfish Cyanea capillata.
Zengliang Ruan, Guoyan Liu, Beilei Wang, Yonghong Zhou, Jia Lu, Qianqian Wang, Jie Zhao, Liming Zhang   +7 more
doaj   +1 more source