Results 121 to 130 of about 95,453 (303)

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

Ginsenoside Rf inhibits cyclooxygenase-2 induction via peroxisome proliferator–activated receptor gamma in A549 cells

Journal of Ginseng Research, 2019
Background: Ginsenoside Rf is a ginseng saponin found only in Panax ginseng that affects lipid metabolism. It also has neuroprotective and antiinflammatory properties.
Heewon Song, Joonwoo Park, KeunOh Choi, Jeonggeun Lee, Jie Chen, Hyun-Ju Park, Byeung-Il Yu, Mitsuru Iida, Mee-Ra Rhyu, YoungJoo Lee   +9 more
doaj   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Pioglitazone: A review of analytical methods

Journal of Pharmaceutical Analysis, 2014
Pioglitazone is an oral anti-hyperglycemic agent. It is used for the treatment of diabetes mellitus type 2. It selectively stimulates nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-gamma).
N. Satheeshkumar, S. Shantikumar, R. Srinivas   +2 more
doaj   +1 more source

Potential therapeutic effects of peroxisome proliferator-activated receptors on corneal diseases

Experimental Biology and Medicine
The cornea is an avascular tissue in the eye that has multiple functions in the eye to maintain clear vision which can significantly impair one’s vision when subjected to damage.
Bing Jie Chow, Isabelle Xin Yu Lee, Chang Liu, Yu-Chi Liu, Yu-Chi Liu, Yu-Chi Liu   +5 more
doaj   +1 more source

Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

EMBO Molecular Medicine, 2017
Lactase (LCT) deficiency affects approximately 75% of the world's adult population and may lead to lactose malabsorption and intolerance. Currently, the regulation of LCT gene expression remains poorly known.
Mathurin Fumery, Silvia Speca, Audrey Langlois, Anne‐Marie Davila, Caroline Dubuquoy, Marta Grauso, Anthony Martin Mena, Martin Figeac, Daniel Metzger, Christel Rousseaux, Jean‐Frederic Colombel, Laurent Dubuquoy, Pierre Desreumaux, Benjamin Bertin   +13 more
doaj   +1 more source

Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats

Marine Drugs, 2018
The present study examined and compared the effects of low- and high-molecular weight (MW) chitosan, a nutraceutical, on lipid metabolism in the intestine and liver of high-fat (HF) diet-fed rats.
Shing-Hwa Liu, Chen-Yuan Chiu, Ching-Ming Shi, Meng-Tsan Chiang   +3 more
doaj   +1 more source

Alternative Transcription of Peroxisome Proliferator-Activated Receptor Gamma in the Liver Is Associated with Fatness of Chickens

Brazilian Journal of Poultry Science
The expression of four transcription variant of peroxisome proliferator-activated receptor gamma gene (PPARG) (XM_015292931.1; XM_015292932.1; XM_015292933.1 and NM_001001460.1) in the liver of broilers was measured and its correlation with abdominal fat
R Parada, T Malewski, K Jaszczak, M Kawka   +3 more
doaj   +1 more source

Synthesized flavone attenuates diabetes‐induced neurodegeneration through regulation of oxidative stress and metabolic‐neurodegenerative molecular pathways

Ibrain, EarlyView.
Neuroprotective efficacy of flavone (2‐phenyl‐4H‐chromen‐4‐one). The study aimed to explore the potential of a synthetic derivative (flavone) of a phytocompound, which is involved in neuroprotection activities. Experimental strategies included the characteristics of compound, in‐silico analysis, and in vivo assessments.
Karishma Sen, Anita Sakarwal, Heera Ram, Suman K. Saha, Nirmal K. Rana, Dharmveer Yadav, Sunil Dutt Shukla, Mukesh Kumar Yadav, Balachandar Vellingiri, Vikas Kumar   +9 more
wiley   +1 more source