Results 101 to 110 of about 105,604 (235)

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly

Clinical Interventions in Aging, 2010
Bodh I JugduttDivision of Cardiology, Department of Medicine, University of Alberta and Hospital, Edmonton, CanadaAbstract: Elderly patients (age≥65 years) with hypertension are at high risk for vascular complications, especially when diabetes is ...
Bodh I Jugdutt
doaj  

Acute hyper-hypoxia accelerates the development of depression in mice via the IL-6/PGC1α/MFN2 signaling pathway

Open Medicine
Neural cell damage is an important cause of exacerbation of depression symptoms caused by hypoxia, but the mechanism behind it is still unclear. The purpose of this study is to elucidate the role of peroxisome proliferator-activated receptor gamma ...
Yu Jialu
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Peroxisome proliferator-activated receptor gamma-2 P12A polymorphism and risk of acute myocardial infarction, coronary heart disease and ischemic stroke: A case-cohort study and meta-analyses

Vascular Health and Risk Management, 2008
Mohammad Hadi Zafarmand1,3, Yvonne T van der Schouw1, Diederick E Grobbee1, Peter W de Leeuw2, Michiel L Bots11Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Heidelberglaan 100, Str 6.131, 3584 CX, Utrecht, The ...
Mohammad Hadi Zafarmand, Yvonne T van der Schouw, Diederick E Grobbee, Peter W de Leeuw, Michiel L Bots   +4 more
doaj  

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator.

Endocrine reviews, 2003
P. Puigserver, B. Spiegelman
semanticscholar   +1 more source

mRNA expressions of peroxisome proliferator-activated receptor gamma coactivator 1α, tumor necrosis factor-α, and interleukin-6 in paraspinal muscles of patients with lumbar kyphosis: a preliminary study

Clinical Interventions in Aging, 2018
Daisuke Kudo, Naohisa Miyakoshi, Michio Hongo, Yuji Kasukawa, Yoshinori Ishikawa, Masashi Fujii, Yoichi Shimada Department of Orthopedic Surgery, Akita University Graduate School of Medicine, Akita, Japan Background: Kyphosis is a spine deformity that ...
Kudo D, Miyakoshi N, Hongo M, Kasukawa Y, Ishikawa Y, Fujii M, Shimada Y   +6 more
doaj  

A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.

Cell, 1995
S. Kliewer, J. Lenhard, T. Willson, Inder Patel, D. Morris, J. Lehmann   +5 more
semanticscholar   +1 more source

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.

Journal of Clinical Investigation, 2000
J. J. Lehman, P. Barger, A. Kovács, J. Saffitz, D. Medeiros, D. Kelly   +5 more
semanticscholar   +1 more source

Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-Alpha

Definitions, 2020
Marcia M. Schilling
semanticscholar   +1 more source