The Role of Peroxisome Proliferator-Activated Receptors in Kidney Diseases [PDF]
Frontiers in Pharmacology, 2022 Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors.
Jianjun Gao, Zhaoyan Gu, Zhaoyan Gu
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Exploring the Role of Peroxisome Proliferator-Activated Receptors and Endothelial Dysfunction in Metabolic Dysfunction-Associated Steatotic Liver Disease [PDF]
CellsThe endothelium is a well known regulator of vascular homeostasis. Several factors can influence the balance of the bioavailability of active substances.
Ana Paula Madariaga Traconis +2 more
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Potential therapeutic effects of peroxisome proliferator-activated receptors on corneal diseases [PDF]
Experimental Biology and MedicineThe cornea is an avascular tissue in the eye that has multiple functions in the eye to maintain clear vision which can significantly impair one’s vision when subjected to damage.
Bing Jie Chow +5 more
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Chondrosarcoma and Peroxisome Proliferator‐Activated Receptor [PDF]
PPAR Research, 2008 Induction of differentiation and apoptosis in cancer cells by ligands of PPARγ is a novel therapeutic approach to malignant tumors. Chondrosarcoma (malignant cartilage tumor) and OUMS‐27 cells (cell line established from grade III human chondrosarcoma) express PPARγ.
K. Hashizume +5 more
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Recent Insights into the Role of PPARs in Disease
Cells, 2023 Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that play important roles in cell proliferation, differentiation, metabolism, and cancer [...]
Nicole Wagner, Kay-Dietrich Wagner
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Metabolic interactions between vitamin A and conjugated linoleic acid [PDF]
, 2014 Lipid-soluble molecules share several aspects of their physiology due to their common adaptations to a hydrophilic environment, and may interact to regulate their action in a tissue-specific manner.
BANNI, SEBASTIANO +7 more
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Regulation of genes involved in carnitine homeostasis by PPARa across different species (rat, mouse, pig, cattle, chicken, and human) [PDF]
, 2012 Recent studies in rodents convincingly demonstrated that PPAR-alpha is a key regulator of genes involved in carnitine homeostasis, which serves as a reasonable explanation for the phenomenon that energy deprivation and fibrate treatment, both of which ...
Egeri, Leonie +4 more
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Variants of the human PPARG locus and the susceptibility to chronic periodontitis [PDF]
, 2011 Apart from its regulatory function in lipid and glucose metabolism, peroxisome proliferator-activated receptor (PPAR)γ has impact on the regulation of inflammation and bone metabolism.
Desvergne B +5 more
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Peroxisome Proliferator-Activated Receptors [PDF]
Hypertension, 2003 Peroxisome proliferator-activated receptors (PPAR) are nuclear receptors acting as transcription factors on numerous target genes after heterodimerization with the retinoid X receptor. PPAR-α and PPAR-γ may be activated by different agonists, although the endogenous ligands are unknown.
Karen L. MacNaul, David E. Moller
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Peroxisome Proliferator–Activated Receptors and The Metabolic Syndrome
Indonesian Biomedical Journal, 2009 BACKGROUND: Obesity is a growing threat to global health by virtue of its association with insulin resistance, inflammation, hypertension, and dyslipidemia, collectively known as the metabolic syndrome (MetS).
Anna Meiliana, Andi Wijaya
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