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Biochimie, 2014 Peroxisomes are essential organelles in higher eukaryotes as they play a major role in numerous metabolic pathways and redox homeostasis. Some peroxisomal abnormalities, which are often not compatible with life or normal development, were identified in severe demyelinating and neurodegenerative brain diseases.
Trompier, Doriane +7 more
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Calcium in peroxisomes: An essential messenger in an essential cell organelle
Frontiers in Cell and Developmental Biology, 2022 Calcium is a central signal transduction element in biology. Peroxisomes are essential cellular organelles, yet calcium handling in peroxisomes has been contentious.
Yelena Sargsyan +5 more
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The proteome of human liver peroxisomes: identification of five new peroxisomal constituents by a label-free quantitative proteomics survey. [PDF]
PLoS ONE, 2013 The peroxisome is a key organelle of low abundance that fulfils various functions essential for human cell metabolism. Severe genetic diseases in humans are caused by defects in peroxisome biogenesis or deficiencies in the function of single peroxisomal ...
Thomas Gronemeyer +12 more
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Emerging nanomaterials for targeting peroxisomes
Materials Today Advances, 2022 Peroxisomes are single membrane-bound metabolic organelles whose dysfunction can lead to several metabolic disorders. In addition, they have been associated with the pathology of several diseases such as cancer, autoimmune diseases, diabetes, stroke, etc.
Akash Bachhuka +5 more
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A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells
iScience, 2020 Summary: Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than 1 h to complete and can be laborious to implement.
G. Jordan Ray +6 more
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Peroxisomal Membrane Contact Sites in Yeasts
Frontiers in Cell and Developmental Biology, 2021 Peroxisomes are ubiquitous, single membrane-bound organelles that play a crucial role in lipid metabolism and human health. While peroxisome number is maintained by the division of existing peroxisomes, nascent peroxisomes can be generated from the ...
Amit S. Joshi
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RhoA regulates peroxisome association to microtubules and the actin cytoskeleton. [PDF]
PLoS ONE, 2010 The current view of peroxisome inheritance provides for the formation of new peroxisomes by both budding from the endoplasmic reticulum and autonomous division.
Lukas Schollenberger +10 more
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Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging
Antioxidants, 2022 Peroxisomes are key regulators of cellular and metabolic homeostasis. These organelles play important roles in redox metabolism, the oxidation of very-long-chain fatty acids (VLCFAs), and the biosynthesis of ether phospholipids.
Jinoh Kim, Hua Bai
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Frontiers in Physiology, 2013 It has long been regarded that the primary function of fungal peroxisomes is limited to the β-oxidation of fatty acids, as mutants lacking peroxisomal function fail to grow in minimal medium containing fatty acids as the sole carbon source.
Jun-ichi eMARUYAMA, Katsuhiko eKITAMOTO
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