Glucose-6-phosphate-dehydrogenase on old peroxisomes maintains self-renewal of epithelial stem cells after asymmetric cell division [PDF]
Nature CommunicationsSelective inheritance of sub-cellular components has emerged as a mechanism guiding stem cell fate after asymmetric cell divisions. Peroxisomes play a crucial role in multiple metabolic processes such as fatty acid metabolism and reactive oxygen species ...
Hien Bui +14 more
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De novo biosynthesis of taxifolin in yeast peroxisomes [PDF]
Microbial Cell FactoriesBackground Yeast peroxisomes have been engineered as ideal synthetic compartments to enhance the heterologous biosynthesis of natural products, particularly terpenoids and fatty acid derivatives.
Qi Wu, Ruibing Chen, Lei Zhang
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Plant peroxisomes: A nitro-oxidative cocktail
Redox Biology, 2017 Although peroxisomes are very simple organelles, research on different species has provided us with an understanding of their importance in terms of cell viability.
Francisco Corpas +2 more
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Calcium in peroxisomes: An essential messenger in an essential cell organelle
Frontiers in Cell and Developmental Biology, 2022 Calcium is a central signal transduction element in biology. Peroxisomes are essential cellular organelles, yet calcium handling in peroxisomes has been contentious.
Yelena Sargsyan +5 more
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The proteome of human liver peroxisomes: identification of five new peroxisomal constituents by a label-free quantitative proteomics survey. [PDF]
PLoS ONE, 2013 The peroxisome is a key organelle of low abundance that fulfils various functions essential for human cell metabolism. Severe genetic diseases in humans are caused by defects in peroxisome biogenesis or deficiencies in the function of single peroxisomal ...
Thomas Gronemeyer +12 more
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Emerging nanomaterials for targeting peroxisomes
Materials Today Advances, 2022 Peroxisomes are single membrane-bound metabolic organelles whose dysfunction can lead to several metabolic disorders. In addition, they have been associated with the pathology of several diseases such as cancer, autoimmune diseases, diabetes, stroke, etc.
Akash Bachhuka +5 more
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Peroxisomal Membrane Contact Sites in Yeasts
Frontiers in Cell and Developmental Biology, 2021 Peroxisomes are ubiquitous, single membrane-bound organelles that play a crucial role in lipid metabolism and human health. While peroxisome number is maintained by the division of existing peroxisomes, nascent peroxisomes can be generated from the ...
Amit S. Joshi
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A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human Cells
iScience, 2020 Summary: Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than 1 h to complete and can be laborious to implement.
G. Jordan Ray +6 more
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RhoA regulates peroxisome association to microtubules and the actin cytoskeleton. [PDF]
PLoS ONE, 2010 The current view of peroxisome inheritance provides for the formation of new peroxisomes by both budding from the endoplasmic reticulum and autonomous division.
Lukas Schollenberger +10 more
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Dengue and Zika Virus Capsid Proteins Contain a Common PEX19-Binding Motif
Viruses, 2022 Flaviviruses such as dengue virus (DENV) and Zika virus (ZIKV) have evolved sophisticated mechanisms to suppress the host immune system. For instance, flavivirus infections were found to sabotage peroxisomes, organelles with an important role in innate ...
Mafalda A. Farelo +5 more
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