Results 31 to 40 of about 42,473 (314)

Implication of peroxisomes and mitochondria in the halophyte Cakile maritima tolerance to salinity stress

open access: yesBiologia Plantarum, 2019
The role of mitochondria and peroxisomes in the tolerance of the halophyte Cakile martima to salt stress was studied. The plants were subjected to 0, 100, and 200 mM NaCl for 5 weeks.
N. Ben Amor   +4 more
doaj   +1 more source

Peroxisomes: The extended shuttle to the peroxisome matrix [PDF]

open access: yesCurrent Biology, 2001
A recent study indicates that protein import into the peroxisomal matrix occurs by a possibly unique mechanism involving the shuttling of cargo receptors into and out of the organelles.
openaire   +3 more sources

Bile acid synthesis in rat liver peroxisomes: metabolism of 26-hydroxycholesterol to 3 beta-hydroxy-5-cholenoic acid

open access: yesJournal of Lipid Research, 1985
Rat liver peroxisomes have been found to oxidize 26-hydroxycholesterol, the product of cholesterol C-26 hydroxylation to 3 beta-hydroxy-5-cholenoic acid.
S K Krisans   +4 more
doaj   +1 more source

Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains

open access: yesActa Neuropathologica Communications, 2023
Peroxisomes are eukaryotic organelles that rapidly change in number depending on the metabolic requirement of distinct cell types and tissues. In the brain, these organelles are essential for neuronal migration and myelination during development and ...
Eugen Semikasev   +4 more
doaj   +1 more source

Peroxisomal Disorders

open access: yesNeurologic Clinics, 1990
Although peroxisomes were once considered a vestige, their importance in cellular metabolism is clearly established by the many inherited diseases that have been described in the past two decades. Unfortunately there is no definitive treatment for the various disorders, but based on the recognition of the biochemical abnormalities, prenatal testing and
S, Naidu, H W, Moser
openaire   +3 more sources

Role of peroxisomes in the oxidative injury induced by 2,4-dichlorophenoxyacetic acid in leaves of pea plants

open access: yesBiologia Plantarum, 2011
The role of peroxisomes in the oxidative injury induced by the auxin herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) in leaves of pea (Pisum sativum L.) plants was studied.
I. McCarthy-Suárez   +3 more
doaj   +1 more source

Peroxisomes and peroxisomal disorders: The main facts [PDF]

open access: yesExperimental and Toxicologic Pathology, 2010
The importance of peroxisomes for human health is highlighted by the number of peroxisomal disorders (PDs), diseases associated to peroxisome biogenesis disorders and peroxisomal enzyme/transporter deficiencies. Currently, many physiological/biosynthetic mechanisms involved in these illnesses have been elucidated, but PDs remain incurable.
openaire   +4 more sources

De novo peroxisome biogenesis in Penicillium chrysogenum is not dependent on the Pex11 family members or Pex16. [PDF]

open access: yesPLoS ONE, 2012
We have analyzed the role of the three members of the Pex11 protein family in peroxisome formation in the filamentous fungus Penicillium chrysogenum. Two of these, Pex11 and Pex11C, are components of the peroxisomal membrane, while Pex11B is present at ...
Łukasz Opaliński   +7 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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