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DNA repair machinery has been found to be indispensable for fluoroquinolone (FQ) persistence of Escherichia coli. Previously, we found that cells harboring two copies of the chromosome (2Chr) in stationary-phase cultures were more likely to yield FQ ...
Juechun Tang +3 more
doaj +2 more sources
Stationary-phase Pseudomonas aeruginosa fluoroquinolone persisters mostly avoid DNA double-stranded breaks [PDF]
When susceptible bacterial cultures are treated with antibiotics, some cells can survive treatment without heritable resistance, giving rise to susceptible daughter cells in a phenomenon termed antibiotic persistence.
Patricia J. Hare +2 more
doaj +2 more sources
Persisters: a distinct physiological state of
Background Bacterial populations contain persisters, phenotypic variants that constitute approximately 1% of cells in stationary phase and biofilm cultures.
Khodursky Arkady B +5 more
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Salmonella enterica persister cells exhibit distinct susceptibility profiles following exposure to human serum and macrophages. [PDF]
Salmonella enterica, particularly non-typhoidal serovars (NTS), is a leading cause of foodborne illness, with invasive infections posing high mortality risks in developing countries.
Rodrigo Lira Rodrigues +8 more
doaj +2 more sources
Bakuchiol kills Staphylococcus aureus persisters and potentiates colistin activity against Acinetobacter baumannii persisters [PDF]
Infections associated with bacterial persisters are challenging to cure because they can evade antibiotics and regrow, often resulting in relapse.
Kayeong Suh +9 more
doaj +2 more sources
Escherichia coli persisters in biofilm can perform horizontal gene transfer by transformation
Persisters represent a subset of cells that exhibit transient tolerance to antimicrobials. These persisters can withstand sudden exposure to antimicrobials, even as the majority of normal cells perish.
Maeda Sumio, Sumio Maeda
exaly +2 more sources
The Synergistic Effect of Exogenous Glutamine and Rifampicin Against Mycobacterium Persisters
Persisters, stochastic dormant variants of normal bacteria cell, represent a significant portion of the survivors upon exposure to antibiotics and other environmental stresses, which contributes substantially to high level antibiotics tolerance ...
Xue Huang +12 more
doaj +2 more sources
Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors.
Marc Schulte +2 more
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Metamorphoses of Lyme disease spirochetes: phenomenon of Borrelia persisters
The survival of spirochetes from the Borrelia burgdorferi (sensu lato) complex in a hostile environment is achieved by the regulation of differential gene expression in response to changes in temperature, salts, nutrient content, acidity fluctuation ...
Natalie Rudenko +3 more
doaj +2 more sources
Fluoroquinolone (FQ)-induced DNA damage in persisters could promote antibiotic resistance. Here, using time-lapse microscopy and genetic analyses, the authors show that after a single round of FQ treatment, SOS response in persisters accelerates the ...
Theresa C. Barrett +3 more
doaj +2 more sources

