Results 71 to 80 of about 616,389 (323)
Prosthetic joint infection (PJI) is a severe complication of arthroplasty. Due to biofilm and persister formation current treatment strategies often fail. Therefore, innovative anti-biofilm and anti-persister agents are urgently needed.
H. Scheper +7 more
semanticscholar +1 more source
Bacterial persisters represent noninheritable drug-tolerant populations that are linked to recalcitrance of infections in health care settings. The rise of antibiotic resistance and the depletion of new antibiotics in the drug discovery pipeline have ...
V. Dubey, Rinki Gupta, R. Pathania
semanticscholar +1 more source
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele +19 more
wiley +1 more source
JUCS - Journal of Universal Computer Science Volume Nr.
Aoto,Takahito, Toyama,Yoshihito
openaire +2 more sources
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut
The emergence of antibiotic-resistant bacteria through mutations or the acquisition of genetic material such as resistance plasmids represents a major public health issue1,2.
Erik Bakkeren +11 more
semanticscholar +1 more source
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Intracellular persister: A stealth agent recalcitrant to antibiotics
The bulk of bacteria transiently evading appropriate antibiotic regimes and recovered from non-resolutive infections are commonly refer to as persisters.
Nicolas Personnic +6 more
doaj +1 more source
Targeting DNA Repair Mechanisms in Bacterial Persisters [PDF]
Bacterial persisters, cells able to survive high concentrations of antimicrobial agents, are problematic in the medical field due to being responsible for recurring infections, and in industrial settings due to causing contamination in pipes. Furthermore,
Saba, Adesola +3 more
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