Results 71 to 80 of about 7,690 (295)

The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress

Communications Biology, 2021
Schulte et al. show that non-replicating Salmonella enterica serovar Typhimurium persisters, which are tolerant to antibiotics, sense their environment and respond to stressors.
Marc Schulte, Katharina Olschewski, Michael Hensel   +2 more
doaj   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Investigating group A Streptococcus antibiotic tolerance in necrotizing fasciitis

mSphere
Group A Streptococcus (GAS) necrotizing fasciitis (NF) is a difficult-to-treat bacterial infection associated with high morbidity and mortality despite extensive surgery and targeted antibiotic treatment.
Nadia Keller, Mathilde Boumasmoud, Federica Andreoni, Andrea Tarnutzer, Manuela von Matt, Thomas C. Scheier, Jana Epprecht, David Weller, Alejandro Gómez-Mejia, Markus Huemer, Donata von Reibnitz, Duveken B. Y. Fontein, Ewerton Marques-Maggio, Reto A. Schuepbach, Srikanth Mairpady-Shambat, Silvio D. Brugger, Annelies S. Zinkernagel   +16 more
doaj   +1 more source

ATP-Dependent Persister Formation in Escherichia coli

mBio, 2017
Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy.
Yue Shan, Autumn Brown Gandt, Sarah E. Rowe, Julia P. Deisinger, Brian P. Conlon, Kim Lewis   +5 more
doaj   +1 more source

The formation of persister cells in stationary-phase cultures of Escherichia coli is associated with the aggregation of endogenous proteins. [PDF]

PLoS ONE, 2013
Persister cells (persisters) are transiently tolerant to antibiotics and usually constitute a small part of bacterial populations. Persisters remain dormant but are able to re-grow after antibiotic treatment.
Daria Leszczynska, Ewelina Matuszewska, Dorota Kuczynska-Wisnik, Beata Furmanek-Blaszk, Ewa Laskowska   +4 more
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Persistent Identification of Instruments

Data Science Journal, 2020
Instruments play an essential role in creating research data. Given the importance of instruments and associated metadata to the assessment of data quality and data reuse, globally unique, persistent and resolvable identification of instruments is crucial.
Markus Stocker, Louise Darroch, Rolf Krahl, Ted Habermann, Anusuriya Devaraju, Ulrich Schwardmann, Claudio D'Onofrio, Ingemar Häggström   +7 more
openaire   +10 more sources

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source

High-Throughput Proteomics Identifies Proteins With Importance to Postantibiotic Recovery in Depolarized Persister Cells

Frontiers in Microbiology, 2019
Bacterial populations produce phenotypic variants called persisters to survive harmful conditions. Persisters are highly tolerant to antibiotics and repopulate environments after the stress has vanished.
Daniel-Timon Spanka, Anne Konzer, Daniel Edelmann, Bork A. Berghoff   +3 more
doaj   +1 more source