Results 81 to 90 of about 616,389 (323)

Family Support for Persisters and Non-Persisters in Louisiana\u27s Adult Basic Education Programs.

open access: yes, 1991
The role that family involvement and the effects of home efforts have on improved student achievement for children is well documented in the literature. The purpose of this study was to determine whether family support should be considered when planning ...
Holmes, Geraldine Hargrove
core   +1 more source

Caseum: a Niche for Mycobacterium tuberculosis Drug-Tolerant Persisters

open access: yesClinical Microbiology Reviews, 2020
Caseum, the central necrotic material of tuberculous lesions, is a reservoir of drug-recalcitrant persisting mycobacteria. Caseum is found in closed nodules and in open cavities connecting with an airway.
Jansy P. Sarathy, V. Dartois
semanticscholar   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

The Persistence of Warps [PDF]

open access: yesSymposium - International Astronomical Union, 1979
Hunter and Toomre (1969) have demonstrated that a simple warp of a stellar disk will damp out within one or two galactic rotation periods due to rapid differential recession of stellar orbits. If, however, the galactic gravitational field is more nearly spherically symmetric, the rate of differential recession is decreased and the warp may persist for ...
Allan D. Tubbs, Robert H. Sanders
openaire   +1 more source

Priestia megaterium cells are primed for surviving lethal doses of antibiotics and chemical stress

open access: yesCommunications Biology
Antibiotic resistant infections kill millions worldwide yearly. However, a key factor in recurrent infections is antibiotic persisters. Persisters are not inherently antibiotic-resistant but can withstand antibiotic exposure by entering a non-dividing ...
Manisha Guha   +2 more
doaj   +1 more source

Molecular Mechanisms Underlying Bacterial Persisters

open access: yes, 2014
All bacteria form persisters, cells that are multidrug tolerant and therefore able to survive antibiotic treatment. Due to the low frequencies of persisters in growing bacterial cultures and the complex underlying molecular mechanisms, the phenomenon has
Gerdes, Kenn, Maisonneuve, Etienne
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa   +8 more
wiley   +1 more source

Persistent progress [PDF]

open access: yesCell, 2021
The highly effective and safe mRNA-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines draw on decades of painstaking research to overcome the many hurdles for delivering, expressing, and avoiding toxicity of therapeutic mRNA. Cell editor Nicole Neuman talked with Dr. Katalin Karikó and Dr.
openaire   +2 more sources

Investigating group A Streptococcus antibiotic tolerance in necrotizing fasciitis

open access: yesmSphere
Group A Streptococcus (GAS) necrotizing fasciitis (NF) is a difficult-to-treat bacterial infection associated with high morbidity and mortality despite extensive surgery and targeted antibiotic treatment.
Nadia Keller   +16 more
doaj   +1 more source

Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus.

open access: yesPLoS Genetics, 2013
When growing populations of bacteria are confronted with bactericidal antibiotics, the vast majority of cells are killed, but subpopulations of genetically susceptible but phenotypically resistant bacteria survive.
Paul J T Johnson, Bruce R Levin
doaj   +1 more source

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