Results 81 to 90 of about 7,690 (295)

Persisters show heritable phenotype and generate bacterial heterogeneity and noise in protein expression [PDF]

, 2009
Persisters are a small subpopulation of bacteria that survive a lethal concentration of antibiotic without antibiotic resistance genes. Isolation of persisters from normally dividing population is considered difficult due to their slow growth, low ...
Jaison Jacob
core  

Persisters killing by antibiotics is more efficient in the presence of osmolytes.

, 2013
To isolate persisters, 24 h stationary culture (LB) was diluted to an OD595 = 0.1 in a fresh LB medium supplemented with amp (200 µg/ml). After 10 h of incubation at 37°C, persisters were pelleted, washed with 0.9% NaCl, resuspended in either M9 medium ...
Daria Leszczynska (287104), Beata Furmanek-Blaszk (287107), Ewelina Matuszewska (287105), Dorota Kuczynska-Wisnik (287106), Ewa Laskowska (287109)   +4 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Factors associated with Persistence despite poor adherence (Discontinuers vs. Persisters who did not take PrEP).

, 2022
Factors associated with Persistence despite poor adherence (Discontinuers vs. Persisters who did not take PrEP).
Daniel Oluoch Madiang (13775725), Ann Duerr (229167), Jean de Dieu Tapsoba (644821), Jane Cover (13775713), Tim R. Cressey (12111519), Gordon Okomo (8062232), Christopher Obong’o (12328760), Paul Drain (6670202), Edward Kariithi (11950293), Rael Obanda (13775722), Kira Mori (13775719), Ying Qing Chen (13775728), Martha Brady (13775716)   +12 more
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Supplementary Table from Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2⁺ Breast Cancer

, 2022
Supplementary Table from Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast ...
Jayu Jen (15103700), Shaowen Jiang (14691341), Allison M.L. Nixon (15120665), Aristotelis Tsirigos (14946172), Alireza Khodadadi-Jamayran (14943034), Azin Sayad (255865), Chewei Anderson Chang (15120659), Jiehui Deng (15044394), Arvind Singh Mer (14959032), Kwan Ho Tang (15054848), Abhyudai Singh (503811), Peter Meyn (15109760), David Venet (15023685), Avantika Dhabaria (1696879), Kwok-kin Wong (14910437), Benjamin Haibe-Kains (14934755), Sylvia Adams (470643), Beatrix Ueberheide (548598), Jane A. Skok (8824274), Christos Sotiriou (15033096), Benjamin G. Neel (162598), Adriana Heguy (596012), Kevin R. Brown (15120662), Jason Moffat (15120668)   +23 more
core   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Persisters: a distinct physiological state of E. coli

BMC Microbiology, 2006
Background Bacterial populations contain persisters, phenotypic variants that constitute approximately 1% of cells in stationary phase and biofilm cultures.
Khodursky Arkady B, Zhang Zhigang, Shah Devang, Kaldalu Niilo, Kurg Kristi, Lewis Kim   +5 more
doaj   +1 more source

Persisters show heritable phenotype and generate bacterial heterogeneity and noise in protein expression [PDF]

, 2007
Persisters are a small subpopulation of bacteria that survive a lethal concentration of antibiotic without antibiotic resistance genes. Isolation of persisters from normally dividing population is considered difficult due to their slow growth, low ...
Jaison Jacob
core  

GhoSTly bacterial persisters.

, 2012
Bacterial persisters consist of a phenotypic subpopulation that survives antibiotic treatment, prolonging infection. The GhoT toxin from the newly discovered ghoS-ghoT toxin-antitoxin system contributes to persistence, most likely by interfering with ...
Van Melderen, Laurence, Laurence Van Melderen   +1 more
core   +1 more source