Results 71 to 80 of about 184,353 (290)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Factors Influencing Job Change Desire: An Empirical Study on Employees in Startup Environments

open access: yesJurnal Manajemen Teori dan Terapan
Objective: The study aimed to investigate and evaluate the impact of person-organization fit (POF), person-job fit (PJF), and person-group fit (PGF) on turnover intention through job satisfaction (JS) in startup companies.
Almirazada Dwiratu Djaganata   +1 more
doaj   +1 more source

Workplace flourishing: Measurement, antecedents and outcomes

open access: yesSA Journal of Industrial Psychology, 2019
Orientation: The continuous growth of employee attrition, especially within the highly skilled talent pool, is becoming increasingly problematic.
Kleinjan Redelinghuys   +2 more
doaj   +1 more source

Person-Environment Fit (PE Fit): Evidence from Brazil

open access: yes, 2019
The purpose of this paper is to investigate if there are positive and significant correlations between the dimensions of Person-Environment Fit (Person-Job, Person-Organization, Person-Group and Person-Supervisor) at the “Best Companies to Work for” in ...
Danielle Deimling De Carli   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Person-environment fit in higher education: how good is the fit for indigenous students? [PDF]

open access: yes, 2002
[Abstract]: [The authors] open this chapter with a brief description of a young Australian Aboriginal student's first year at University. Her story is typical of the experiences of many Indigenous students attempting to come to grips with life away from ...
White, Colin, Fogarty, Gerard J.
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of working environment perception and person⁃organization fit on transition shock of newly recruited nurses with bachelor degree or above

open access: yesHuli yanjiu, 2021
ObjectiveTo explore the effect of working environment perception and person⁃organization fit on transition shock of newly recruited nurses with bachelor degree or above.MethodsTotally 367 newly recruited nurses from a tertiary A hospital in Henan ...
ZHANG Panpan   +4 more
doaj  

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