Results 121 to 130 of about 290,324 (267)

Practical Person-Fit Assessment with the Linear FA Model: New Developments and a Comparative Study. [PDF]

Front Psychol, 2016
Ferrando PJ, Vigil-Colet A, Lorenzo-Seva U.   +2 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Reducing Calibration Bias for Person Fit Assessment by Mixture Model Expansion. [PDF]

Educ Psychol Meas
Braeken J, van Laar S.
europepmc   +1 more source

Derivation and Applicability of Asymptotic Results for Multiple Subtests Person-Fit Statistics. [PDF]

Appl Psychol Meas, 2016
Albers CJ, Meijer RR, Tendeiro JN.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Model-Based Person Fit Statistics Applied to the Wechsler Adult Intelligence Scale IV. [PDF]

Educ Psychol Meas
Block JM, Reise SP, Widaman KF, Montoya AK, Loring DW, Glass Umfleet L, Bauer RM, Gullett JM, Wolff B, Drane DL, Enriquez K, Bilder RM.   +11 more
europepmc   +1 more source

Identifying Person-Fit Latent Classes, and Explanation of Categorical and Continuous Person Misfit. [PDF]

Appl Psychol Meas, 2016
Conijn JM, Sijtsma K, Emons WHM.
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Enhancing the Detection of Social Desirability Bias Using Machine Learning: A Novel Application of Person-Fit Indices. [PDF]

Educ Psychol Meas
Nazari S, Leite WL, Huggins-Manley AC.
europepmc   +1 more source