FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Evaluating Person Fit for Cognitive Diagnostic Assessment. [PDF]
Appl Psychol Meas, 2015 Cui Y, Li J.
europepmc +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Practical Person-Fit Assessment with the Linear FA Model: New Developments and a Comparative Study. [PDF]
Front Psychol, 2016 Ferrando PJ +2 more
europepmc +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Reducing Calibration Bias for Person Fit Assessment by Mixture Model Expansion. [PDF]
Educ Psychol MeasBraeken J, van Laar S.
europepmc +1 more source
Derivation and Applicability of Asymptotic Results for Multiple Subtests Person-Fit Statistics. [PDF]
Appl Psychol Meas, 2016 Albers CJ, Meijer RR, Tendeiro JN.
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Model-Based Person Fit Statistics Applied to the Wechsler Adult Intelligence Scale IV. [PDF]
Educ Psychol MeasBlock JM +11 more
europepmc +1 more source
Identifying Person-Fit Latent Classes, and Explanation of Categorical and Continuous Person Misfit. [PDF]
Appl Psychol Meas, 2016 Conijn JM, Sijtsma K, Emons WHM.
europepmc +1 more source