Results 31 to 40 of about 1,944 (186)

Proteome Dynamics of Persulfidation in Leaf Tissue under Light/Dark Conditions and Carbon Deprivation

Antioxidants, 2023
Hydrogen sulfide (H2S) acts as a signaling molecule in plants, bacteria, and mammals, regulating various physiological and pathological processes.
Ana Jurado-Flores, Cecilia Gotor, Luis C. Romero   +2 more
doaj   +1 more source

Evidence of endogenously produced hydrogen sulfide (H2S) and persulfidation in male reproduction

Scientific Reports, 2022
Persulfidation contributes to a group of redox post-translational modifications (PTMs), which arise exclusively on the sulfhydryl group of cysteine as a result of hydrogen sulfide (H2S) action.
Hedvika Řimnáčová, Jiří Moravec, Miriama Štiavnická, Jiřina Havránková, Ladan Monsef, Petr Hošek, Šárka Prokešová, Tereza Žalmanová, Tereza Fenclová, Jaroslav Petr, Milena Králíčková, Jan Nevoral   +11 more
doaj   +1 more source

The Combined Partial Knockdown of CBS and MPST Genes Induces Inflammation, Impairs Adipocyte Function-Related Gene Expression and Disrupts Protein Persulfidation in Human Adipocytes

Antioxidants, 2022
Recent studies in mice and humans demonstrated the relevance of H2S synthesising enzymes, such as CTH, CBS, and MPST, in the physiology of adipose tissue and the differentiation of preadipocyte into adipocytes.
Jessica Latorre, Angeles Aroca, José Manuel Fernández-Real, Luis C. Romero, José María Moreno-Navarrete   +4 more
doaj   +1 more source

3-Mercaptopyruvate sulfur transferase is a protein persulfidase [PDF]

, 2023
Protein S-persulfidation (P-SSH) is recognized as a common posttranslational modification. It occurs under basal conditions and is often observed to be elevated under stress conditions. However, the mechanism(s) by which proteins are persulfidated inside
Barayeu, Uladzimir, Dick, Tobias P., Glatt, Sebastian, Luzarowski, Marcin, Pedre, Brandán, Schilling, Danny, Sokołowski, Mikołaj, Talwar, Deepti   +7 more
core   +3 more sources

Emerging Chemical Biology of Protein Persulfidation

Antioxidants & Redox Signaling, 2023
Significance: Protein persulfidation (the formation of RSSH), an evolutionarily conserved oxidative posttranslational modification in which thiol groups in cysteine residues are converted into persulfides, has emerged as one of the main mechanisms through which hydrogen sulfide (H2S) conveys its signaling.
Vignane, Thibaut, Filipovic, Milos R.
openaire   +2 more sources

The Hepatic Compensatory Response to Elevated Systemic Sulfide Promotes Diabetes [PDF]

, 2021
Impaired hepatic glucose and lipid metabolism are hallmarks of type 2 diabetes. Increased sulfide production or sulfide donor compounds may beneficially regulate hepatic metabolism.
Banerjee, Ruma, Barrios-Llerena, Martin E., Briand, Francois, Brice, Madara, Denham, Scott G., Emerson, Barry, Faresse, Nourdine, Freddolino, Peter L., Gibbins, Matthew T G, Gillingwater, Thomas H, Gray, Gillian A, Han Ahn, Kyo, Hartley, Richard C, Homer, Natalie Z M, J Finch, Andrew, Le Bihan, Thierry, Libiad, Marouane, McFadden, Clare, McMaster, Claire, Morton, Nicholas M, Nicholas Carter, Roderick, Selman, Colin, Singha, Subhankar, Staels, Bart, Su, Huizhong, Sulpice, Thierry, Tailleux, Anne, Vitvitsky, Victor, Wilkie, Stephen E   +28 more
core   +5 more sources

Acidity and nucleophilic reactivity of glutathione persulfide [PDF]

Journal of Biological Chemistry, 2020
Les persulfures (RSSH/RSS−) participent au trafic de soufre et aux processus métaboliques, et sont proposés pour médier les effets de signalisation du sulfure d'hydrogène (H2S). Malgré leur pertinence croissante, leurs propriétés chimiques sont mal comprises.
Dayana Benchoam, Jonathan A. Semelak, Ernesto Cuevasanta, Mauricio Mastrogiovanni, Juan Santiago Grassano, Gerardo Ferrer‐Sueta, Ari Zeida, Madia Trujillo, Matías N. Möller, Darío A. Estrı́n, Beatriz Álvarez   +10 more
openaire   +4 more sources

The Modus Operandi of Hydrogen Sulfide(H₂S)-Dependent Protein Persulfidation in Higher Plants

Antioxidants, 2021
Protein persulfidation is a post-translational modification (PTM) mediated by hydrogen sulfide (H2S), which affects the thiol group of cysteine residues from target proteins and can have a positive, negative or zero impact on protein function.
Francisco J. Corpas, Salvador González-Gordo, María A. Muñoz-Vargas, Marta Rodríguez-Ruiz, José M. Palma   +4 more
doaj   +1 more source

A Proteomic Approach to Study the Effect of Thiotaurine on Human Neutrophil Activation [PDF]

, 2017
Thiotaurine, a thiosulfonate related to taurine and hypotaurine, is formed by a metabolic process from cystine and generated by a transulfuration reaction between hypotaurine and thiocysteine.
A Ferrante, AK Mustafa, B Sörbo, BD Paul, BD Paul, C De Marco, C De Marco, D Cavallini, D Cavallini, D Cavallini, DB Learn, E Capuozzo, E Capuozzo, E Cuevasanta, EG Mueller, F Di Domenico, GX Luo, H Beinert, H Kimura, J Dragotto, J Westley, JI Toohey, JI Toohey, L Cattaneo, M Whiteman, M Whiteman, MR Hara, O Kabil, PK Yadav, RCO Zanardo, S Canterini, S Singh, TR Chauncey, TV Mishanina   +33 more
core   +2 more sources

Recent Development of the Molecular and Cellular Mechanisms of Hydrogen Sulfide Gasotransmitter

Antioxidants, 2022
Hydrogen sulfide has been recently identified as the third biological gasotransmitter, along with the more well studied nitric oxide (NO) and carbon monoxide (CO). Intensive studies on its potential as a therapeutic agent for cardiovascular, inflammatory,
Jianyun Liu, Fikir M. Mesfin, Chelsea E. Hunter, Kenneth R. Olson, W. Christopher Shelley, John P. Brokaw, Krishna Manohar, Troy A. Markel   +7 more
doaj   +1 more source