Results 81 to 90 of about 1,944 (186)
The Journal of Physiology, EarlyView.Abstract figure legend Sodium thiosulfate (STS) rescues the pronephros phenotype of pdx1 morphants through compensatory upregulation of nitric oxide (NO) metabolism. Zebrafish larvae injected with a control morpholino show the typical pronephros structure at 48 h post‐fertilization (hpf) with and without STS treatment.
Hannes Ott +6 more
wiley +1 more source
Structural and Mechanistic Insights into Hemoglobincatalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products [PDF]
, 2017 Hydrogen sulfide is a cardioprotective signaling molecule but is toxic at elevated concentrations. Red blood cells can synthesize H2S but, lacking organelles, cannot dispose of H2S via the mitochondrial sulfide oxidation pathway.
An, Sojin +5 more
core +6 more sources
Redox BiologyAcute inflammatory responses often involve the production of reactive oxygen and nitrogen species by innate immune cells, particularly macrophages. How activated macrophages protect themselves in the face of oxidative-inflammatory stress remains a long ...
Talal Salti +4 more
doaj +1 more source
Proline, Cysteine and Branched-Chain Amino Acids in Abiotic Stress Response of Land Plants and Microalgae [PDF]
, 2023 Proteinogenic amino acids are the building blocks of protein, and plants synthesize all of them. In addition to their importance in plant growth and development, growing evidence underlines the central role played by amino acids and their derivatives in ...
Gurrieri, Libero +4 more
core +1 more source
Linking Superoxide Production and Scavenging in Plant Development
Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
Neoplasia: An International Journal for Oncology Research, 2021 Increased xCT and transsulfuration pathway has been associated with metabolic reprogramming of colorectal cancer. However, the correlation between these 2 events and the underlying molecular mechanism remains obscure.
Shanwen Chen +8 more
doaj +1 more source
Lifespan‐Extending Endogenous Metabolites
Aging Cell, Volume 25, Issue 2, February 2026.Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Enzymology of H2S Biogenesis, Decay and Signaling [PDF]
, 2013 Significance: Hydrogen sulfide (H2S), produced by the desulfuration of cysteine or homocysteine, functions as a signaling molecule in an array of physiological processes including regulation of vascular tone, the cellular stress response, apoptosis, and ...
Banerjee, Ruma, Kabil, Omer
core +1 more source
Protein persulfidation in plants : Mechanisms and functions beyond a simple stress response [PDF]
Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge ...
Meyer, Andreas J. +2 more
core +1 more source
Formation of persulfide groups in alkaline treated insulin [PDF]
FEBS Letters, 1970 Alkaline treatment of disulfidecontaining proteins is known to produce a number of unusual compounds related with the degradation of the cystinyl residues. Lanthionine [l] and lysinoalanine [2] are among the products identified with certainly, while dehydroala- nine [2] , thiocysteine [3,4] , cysteine sulfenic acid [S] and other products are supposed ...
Cavallini, D. +3 more
openaire +2 more sources