Results 11 to 20 of about 2,511 (170)
Protocol for using organic persulfides to measure the chemical reactivity of persulfide sensors
STAR Protocols, 2022 Summary: Hydrogen sulfide (H2S) and downstream reactive sulfur species (RSS), including organic persulfides, protect bacterial cells against diverse oxidative stressors.
Joseph N. Fakhoury +2 more
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Persulfidation of DJ-1: Mechanism and Consequences
Biomolecules, 2022 DJ-1 (also called PARK7) is a ubiquitously expressed protein involved in the etiology of Parkinson disease and cancers. At least one of its three cysteine residues is functionally essential, and its oxidation state determines the specific function of the
Erwan Galardon +5 more
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Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells
Redox Biology, 2021 The cellular effects of hydrogen sulfide (H2S) signaling may be partially mediated by the formation of alkyl persulfides from thiols, such as glutathione and protein cysteine residues.
Christopher H. Switzer +3 more
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Antioxidants, 2021 Persulfide, polysulfide and thiosulfate are examples of sulfane sulfur containing chemicals that play multiple functions in biological systems. Rhodaneses are widely present in all three kingdoms of life, which catalyze sulfur transfer among these ...
Qingda Wang +4 more
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Protein Persulfidation in Plants: Function and Mechanism [PDF]
Antioxidants, 2021 As an endogenous gaseous transmitter, the function of hydrogen sulfide (H2S) has been extensively studied in plants. Once synthesized, H2S may be involved in almost all life processes of plants. Among them, a key route for H2S bioactivity occurs via protein persulfidation, in which process oxidizes cysteine thiol (R-SH) groups into persulfide (R-SSH ...
Peng Wang +3 more
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Possible molecular basis of the biochemical effects of cysteine-derived persulfides
Frontiers in Molecular Biosciences, 2022 Persulfides (RSSH/RSS−) are species closely related to thiols (RSH/RS−) and hydrogen sulfide (H2S/HS−), and can be formed in biological systems in both low and high molecular weight cysteine-containing compounds.
Ernesto Cuevasanta +15 more
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Contribution of NRF2 to sulfur metabolism and mitochondrial activity
Redox Biology, 2023 NF-E2-related factor 2 (NRF2) plays a crucial role in the maintenance of cellular homeostasis by regulating various enzymes and proteins that are involved in the redox reactions utilizing sulfur.
Md Morshedul Alam +7 more
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Persulfides and the cellular thiol landscape [PDF]
Proceedings of the National Academy of Sciences, 2014 The biochemistry of sulfur touches on every aspect of cellular biology, from protein structure and function to redox regulation to defense against chemical stress. Over the last decade, posttranslational modification of protein thiols by reactive oxygen or nitrogen species has emerged as a major component of signal transduction, leading to both ...
Miranda, Katrina M., Wink, David A.
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Frontiers in Neuroscience, 2022 Friedreich’s ataxia (FRDA) is the most prevalent autosomic recessive ataxia and is associated with a severe cardiac hypertrophy and less frequently diabetes.
Beata Monfort +3 more
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THE PREPARATION AND PROPERTIES OF THE PERSULFIDES OF HYDROGEN. [PDF]
Journal of the American Chemical Society, 1921 n ...
Walton, James H., Parsons, Llewellyn B.
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