Is aldehyde dehydrogenase inhibited by sulfur compounds? In vitro and in vivo studies [PDF]
, 2018 Aldehyde dehydrogenase (ALDH) catalyzes the critical step of ethanol metabolism, i.e. transformation of toxic acetaldehyde to acetic acid. It is a redox sensitive protein with the key Cys in its active site. Recently, it has been documented that activity
Bilska-Wilkosz, Anna +3 more
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Anomalous Kv 7 channel activity in human malignant hyperthermia syndrome unmasks a key role for H2 S and persulfidation in skeletal muscle. [PDF]
BACKGROUND AND PURPOSE: Human malignant hyperthermia (MH) syndrome is induced by volatile anaesthetics and involves increased levels of cystathionine β-synthase (CBS)-derived H2 S within skeletal muscle.
Basso Elisabetta, Maria +15 more
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酸化ストレス下におけるセンサータンパク質の酸化修飾の可逆性に対するパーサルフィド/ポリサルフィドの役割 [PDF]
, 2020 筑波大学University of Tsukuba博士（医学）Doctor of Philosophy in Medical Sciences2019この博士論文は内容の要約のみの公開（または一部非公開）になっていますdoctoral ...
220636 +2 more
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Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension [PDF]
, 2019 Chronic hypoxia causes pulmonary hypertension (PH), vascular remodelling, right ventricular (RV) hypertrophy and cardiac failure. Protein kinase G Iα (PKGIα) is susceptible to oxidation, forming an inter-protein disulfide homodimer associated with kinase
Akaike, Takaaki +13 more
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mSphere, 2017 Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H2S) and nitric oxide (NO·) protect S.
Hui Peng +10 more
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Molecular analysis of the distribution and phylogeny of the soxB gene among sulfur-oxidizing bacteria - evolution of the Sox sulfur-oxidizing enzyme system [PDF]
, 2007 The soxB gene encodes the SoxB component of the periplasmic thiosulfate-oxidizing Sox enzyme complex, which has been proposed to be widespread among the various phylogenetic groups of sulfur-oxidizing bacteria (SOB) that convert thiosulfate to sulfate ...
Brinkhoff T. +13 more
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Redox Biology, 2018 Several diseases are associated with perturbations in redox signaling and aberrant hydrogen sulfide metabolism, and numerous analytical methods exist for the measurement of the sulfur-containing species affected.
T.R. Sutton +11 more
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Protein persulfidation in plants : Mechanisms and functions beyond a simple stress response [PDF]
Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge ...
Meyer, Andreas J. +2 more
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Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]
, 2015 This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna +3 more
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Hydrogen Sulfide: A Potential Novel Therapy for the Treatment of Ischemia [PDF]
, 2017 Hydrogen sulfide (H2S) is a novel signaling molecule most recently found to be of fundamental importance in cellular function as a regulator of apoptosis, inflammation, and perfusion. Mechanisms of endogenous H2S signaling are poorly understood; however,
Drucker, Natalie A. +2 more
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