Results 41 to 50 of about 1,224 (162)

Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?

Redox Biology, 2023
Earlier studies revealed the presence of cysteine persulfide (CysSSH) and related polysulfide species in various mammalian tissues. CysSSH has both antioxidant and oxidant properties, modulates redox-dependent signal transduction and has been shown to ...
Kayleigh Griffiths, Tomoaki Ida, Masanobu Morita, Reece J. Lamb, Jordan J. Lee, Michael P. Frenneaux, Jon M. Fukuto, Takaaki Akaike, Martin Feelisch, Melanie Madhani   +9 more
doaj   +1 more source

Using resonance synchronous spectroscopy to characterize the reactivity and electrophilicity of biologically relevant sulfane sulfur

Redox Biology, 2019
Sulfane sulfur is common inside cells, playing both regulatory and antioxidant roles. However, there are unresolved issues about its chemistry and biochemistry.
Huanjie Li, Huaiwei Liu, Zhigang Chen, Rui Zhao, Qingda Wang, Mingxue Ran, Yongzhen Xia, Xin Hu, Jihua Liu, Ming Xian, Luying Xun   +10 more
doaj   +1 more source

S-sulfhydration of SIRT3 combats BMSC senescence and ameliorates osteoporosis via stabilizing heterochromatic and mitochondrial homeostasis

Pharmacological Research, 2023
Senescence of bone marrow mesenchymal stem cells (BMSCs) is one of the leading causes of osteoporosis. SIRT3, an essential NAD-dependent histone deacetylase, is highly correlated with BMSC senescence-mediated bone degradation and mitochondrial ...
Fei Liu, Longhui Yuan, Lan Li, Jingchao Yang, Jingping Liu, Younan Chen, Jie Zhang, Yanrong Lu, Yujia Yuan, Jingqiu Cheng   +9 more
doaj   +1 more source

Catalytic Sulfur‐Atom Transfer Enabled by a Bis(disulfide) Titanium Complex

Angewandte Chemie International Edition, EarlyView.
Multi‐electron transformations with titanium are underexplored due to limited access to low‐valent precursors. The four‐electron activation of elemental sulfur by a Ti(IV) complex yields a rare titanium bis(disulfide) complex, enabling the efficient catalytic synthesis of isothiocyanates from isonitriles under mild conditions.
Sebastian Samir Cremer, Peter Coburger, Corinna Czernetzki, Gabriele Hierlmeier   +3 more
wiley   +1 more source

Über Persulfide von Aldehyden [PDF]

Journal für Praktische Chemie, 1910
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Bugge, Günther, Bloch, Ignaz
openaire   +1 more source

Supersulfide donors and their therapeutic targets in inflammatory diseases

Frontiers in Immunology
Inflammation is one defense mechanism of the body that has multiple origins, ranging from physical agents to infectious agents including viruses and bacteria.
Tianli Zhang, Yuexuan Pan, Tomohiro Sawa, Takaaki Akaike, Takaaki Akaike, Tetsuro Matsunaga, Tetsuro Matsunaga   +6 more
doaj   +1 more source

Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

Redox Biology, 2017
Many physiological functions of hydrogen sulfide (H2S) have been reported in mammalian cells over the last 20 years. These physiological effects have been ascertained through in vitro treatment of cells with Na2S or NaHS, both of which are precursors of ...
Shin Koike, Shoichi Nishimoto, Yuki Ogasawara   +2 more
doaj   +1 more source

Oral Administration of Glutathione Trisulfide Increases Reactive Sulfur Levels in Dorsal Root Ganglion and Ameliorates Paclitaxel-Induced Peripheral Neuropathy in Mice

Antioxidants, 2022
Peripheral neuropathy is a dose-limiting side effect of chemotherapy with paclitaxel. Paclitaxel-induced peripheral neuropathy (PIPN) is typically characterized by a predominantly sensory neuropathy presenting with allodynia, hyperalgesia and spontaneous
Mariko Ezaka, Eizo Marutani, Yusuke Miyazaki, Eiki Kanemaru, Martin K. Selig, Sophie L. Boerboom, Katrina F. Ostrom, Anat Stemmer-Rachamimov, Donald B. Bloch, Gary J. Brenner, Etsuo Ohshima, Fumito Ichinose   +11 more
doaj   +1 more source

Mining proteomes for zinc finger persulfidation. [PDF]

RSC Chem Biol
A meta-analysis of 22 persulfide-specific proteomics datasets reveals widespread persulfidation of zinc finger proteins across various species, highlighting the role of persulfidation as an important post-translational modification.
Li H, Stoltzfus AT, Michel SLJ.
europepmc   +3 more sources

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source