Results 31 to 40 of about 1,224 (162)
Persulfide Biosynthesis Conserved Evolutionarily in All Organisms. [PDF]
Antioxid Redox Signal, 2023 Significance: Persulfides/polysulfides are sulfur-catenated molecular species ( i.e. , R-S n -R′, n > 2; R-S n
Ogata S +5 more
europepmc +3 more sources
Proteomics Profiling of S-sulfurated Proteins in Acinetobacter baumannii
Bio-Protocol, 2021 Hydrogen sulfide (H2S) is emerging as an important modulator in bacterial cytoprotection against the host immune response in infected animals, which may well be attributed to downstream highly oxidized sulfur species, termed reactive sulfur species (RSS),
Brenna Walsh, David Giedroc
doaj +1 more source
Emerging Chemical Biology of Protein Persulfidation
Antioxidants & Redox Signaling, 2023 Significance: Protein persulfidation (the formation of RSSH), an evolutionarily conserved oxidative posttranslational modification in which thiol groups in cysteine residues are converted into persulfides, has emerged as one of the main mechanisms through which hydrogen sulfide (H
Vignane, Thibaut, Filipovic, Milos R.
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Development of an anti-oxidative intraocular irrigating solution based on reactive persulfides
Scientific Reports, 2022 Anti-oxidative intraocular irrigating solutions (IISs) based on reactive persulfides, such as oxidized glutathione disulfide (GSSG), are commonly used worldwide. However, even with GSSG-based IISs, it has been shown that oxidative stress can occur during
Hiroshi Kunikata +4 more
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The Role of Protein Persulfidation in Brain Aging and Neurodegeneration [PDF]
Frontiers in Aging Neuroscience, 2021 Hydrogen sulfide (H2S), originally considered a toxic gas, is now a recognized gasotransmitter. Numerous studies have revealed the role of H2S as a redox signaling molecule that controls important physiological/pathophysiological functions. The underlying mechanism postulated to serve as an explanation of these effects is protein persulfidation (P-SSH,
Petrovic, Dunja +3 more
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Persulfidation is the mechanism underlying sulfide-signaling of autophagy [PDF]
Autophagy, 2021 In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved
Gotor, Cecilia +2 more
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Biosynthesis and Reactivity of Cysteine Persulfides in Signaling [PDF]
Journal of the American Chemical Society, 2015 Hydrogen sulfide (H2S) elicits pleiotropic physiological effects ranging from modulation of cardiovascular to CNS functions. A dominant method for transmission of sulfide-based signals is via posttranslational modification of reactive cysteine thiols to persulfides. However, the source of the persulfide donor and whether its relationship to H2S is as a
Pramod K, Yadav +6 more
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A concise synthesis of alkyl, aryl hydropersulfides [PDF]
RSC AdvancesA concise synthesis of alkyl- and aryl-hydropersulfides has been developed. This process involves N-thioacetyl succinimide-mediated synthesis of acetyl persulfides and their subsequent deacetylation.
Shishir Bhowmik, Jun Yong Kang
doaj +1 more source
Sulfane Sulfur Compounds as Source of Reappearance of Reductive Off-Odors in Wine
Fermentation, 2022 Reactive compounds with one or more sulfane sulfur atoms can be an important source of reductive off-odors in wine. These substances contain labile sulfur, which can participate in microbiological (enzymatic) and chemical transformations (including in ...
Nikolaus Müller +2 more
doaj +1 more source
Thioredoxin Profiling of Multiple Thioredoxin-Like Proteins in Staphylococcus aureus
Frontiers in Microbiology, 2018 Hydrogen sulfide (H2S) is thought to signal through protein S-sulfuration (persulfidation; S-sulfhydration) in both mammalian systems and bacteria. We previously profiled proteome S-sulfuration in Staphylococcus aureus (S.
Hui Peng +7 more
doaj +1 more source