Results 91 to 100 of about 51,251 (208)
Tolerance without clonal expansion: Self-antigen-expressing B cells program self-reactive T cells for future deletion [PDF]
, 2008 B cells have been shown in various animal models to induce immunological tolerance leading to reduced immune responses and protection from autoimmunity.
Anderton, Stephen M. +9 more
core +1 more source
European Journal of Haematology, Volume 116, Issue 4, Page 336-349, April 2026.ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot +3 more
wiley +1 more source
BMC Pediatrics, 2018 Background Vaccination is still one of the most important methods to control and prevent childhood infections including diphtheria and pertussis. This study evaluated the level of diphtheria (DT) and pertussis (PT)-related antibodies among children with ...
Qinghong Meng +7 more
doaj +1 more source
Iranian Journal of Microbiology, 2020 Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati +3 more
doaj +1 more source
Immunology, Volume 177, Issue 4, Page 784-797, April 2026.This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si +4 more
wiley +1 more source
Neurogastroenterology &Motility, Volume 38, Issue 4, April 2026.Short‐chain fatty acids (SCFAs), including propionate, acetate, and butyrate, activate IPANs and myenteric neurons and delay colonic motility via FFAR2 and FFAR3. GLPG0976 and β‐hydroxybutyrate (BHB) were used as selective antagonists for FFAR2 and FFAR3, respectively, to confirm receptor‐specific effects.
Preedajit Wongkrasant +4 more
wiley +1 more source
Do anionic phospholipids serve as cofactors or second messengers for the regulation of activity of cloned ATP-sensitive K+ channels? [PDF]
, 2003 The regulation of ion channels by anionic phospholipids is currently very topical. An outstanding issue is whether phosphatidylinositol 4,5-diphosphate and related species act as true second messengers in signaling or behave in a manner analogous to an ...
Clapp, LH +4 more
core +1 more source
Understanding the Epidemiology of Pertussis in Denmark
Acta Paediatrica, EarlyView.
Tine Dalby +2 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 3, Page 520-531, March 2026.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Effect of 40 Hz Light Stimulation on Calcium Dynamics of Astrocytes
Advanced Photonics Research, Volume 7, Issue 3, March 2026.40 Hz invisible spectral flickering (ISF) visible light stimulation and continuous light trigger calcium dynamics in primary astrocytes but recruit different signaling pathways. Astrocytes are glial cells with intracellular calcium dynamics essential for brain homeostasis, synaptic modulation, and cognition and altered in neuropathology and ...
Aikaterini Konstantoulaki +9 more
wiley +1 more source