Results 11 to 20 of about 29,628 (214)
Bordetella pertussis Strain Lacking Pertactin and Pertussis Toxin [PDF]
Emerging Infectious Diseases, 2016 A Bordetella pertussis strain lacking 2 acellular vaccine immunogens, pertussis toxin and pertactin, was isolated from an unvaccinated infant in New York State in 2013.
Margaret M. Williams +6 more
doaj +3 more sources
Secretion of Pertussis Toxin from Bordetella pertussis. [PDF]
Toxins (Basel), 2021 Production and secretion of pertussis toxin (PT) is essential for the virulence of Bordetella pertussis. Due to the large oligomeric structure of PT, transport of the toxin across bacterial membrane barriers represents a significant hurdle that the bacteria must overcome in order to maintain pathogenicity.
Burns DL.
europepmc +5 more sources
Novel Strategies to Inhibit Pertussis Toxin. [PDF]
Toxins (Basel), 2022 Pertussis, also known as whooping cough, is a respiratory disease caused by infection with Bordetella pertussis, which releases several virulence factors, including the AB-type pertussis toxin (PT). The characteristic symptom is severe, long-lasting paroxysmal coughing.
Ernst K.
europepmc +6 more sources
New combination of methods for isolation and purification of pertussis toxin from the Bordetella pertussis culture [PDF]
Hemijska Industrija, 2011 In this paper a method for isolation and purification of the pertussis toxin from the cell culture of Bordetella pertussis was presented. Pertussis toxin production was enhanced with the optimization of the microbiological media and cultivation time ...
Pavlović Katarina B. +1 more
doaj +1 more source
mBio, 2020 Dermonecrotic toxin (DNT) is one of the representative toxins produced by Bordetella pertussis, but its role in pertussis, B. pertussis infection, remains unknown.
Shihono Teruya +13 more
doaj +1 more source
Toxins, 2021 The antigens for acellular pertussis vaccines are made up of protein components that are purified directly from Bordetella pertussis (B. pertussis) bacterial fermentation. As such, there are additional B.
Lisa Szymkowicz +4 more
doaj +1 more source
Evaluation of Pertussis Toxin Expression in B2 and THIJS Media [PDF]
Archives of Razi Institute, 2019 Whole-cell pertussis vaccine (wP) has been imperative and highly effective in preventing childhood deaths due to pertussis. Pertussis toxin is one of the virulence factors of Bordetella pertussis in all available pertussis vaccines. wP production in Razi
H. Moradtalab +3 more
doaj +1 more source
Неонатологія, хірургія та перинатальна медицина, 2023 Coronavirus disease remains one of the most serious diseases in the world. The percentage of severe and fatal cases in children is lower than in adults. The search for biomarkers of disease severity continues.
Г. Павлишин +2 more
doaj +1 more source
Alpha-1 antitrypsin inhibits pertussis toxin. [PDF]
J Biol ChemPertussis (whooping cough) is a vaccine-preventable but re-emerging, highly infectious respiratory disease caused by Bordetella pertussis. There are currently no effective treatments for pertussis, complicating care for nonvaccinated individuals, especially newborns.
Lietz S +20 more
europepmc +3 more sources