Results 31 to 40 of about 33,335 (199)

Protective Activity and Safety of Acellular Pertussis Vaccine from Vaccine and Freshly Isolated Strain Bordetella pertussis

open access: yesЭпидемиология и вакцинопрофилактика, 2017
Goal. Study of the protective activity and safety of acellular pertussis vaccine (APV) using freshly isolated strain of B. pertussis. Materials and methods. Mice-hybrids F1 (CBAxC57Bl6). The B. pertussis strains: vaccine strains No. 305, No. 203, freshly
E. M. Zaitsev   +2 more
doaj   +1 more source

Differentially expressed genes in Bordetella pertussis strains belonging to a lineage which recently spread globally. [PDF]

open access: yesPLoS ONE, 2014
Pertussis is a highly contagious, acute respiratory disease in humans caused by the Gram-negative pathogen Bordetella pertussis. Pertussis has resurged in the face of intensive vaccination and this has coincided with the emergence of strains carrying a ...
Daan de Gouw   +6 more
doaj   +1 more source

Online automatic tuning and control for fed-batch cultivation [PDF]

open access: yes, 2007
Performance of controllers applied in biotechnological production is often below expectation. Online automatic tuning has the capability to improve control performance by adjusting control parameters.
Straten, G., van   +7 more
core   +1 more source

G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. [PDF]

open access: yesPLoS ONE, 2009
BACKGROUND:Reprogramming adult human somatic cells to create human induced pluripotent stem (hiPS) cell colonies involves a dramatic morphological and organizational transition.
Kenta Nakamura   +4 more
doaj   +1 more source

Pertussis in Lao PDR: Seroprevalence and disease [PDF]

open access: yes, 2020
Objectives Pertussis is a debilitating vaccine-preventable infection. The aim of this study was to determine susceptibility and exposure to pertussis in Lao PDR in different age groups and subpopulations.
Chanthavilay, Phetsavanh   +9 more
core   +1 more source

Integrating proteomic data with metabolic modeling provides insight into key pathways of Bordetella pertussis biofilms

open access: yesFrontiers in Microbiology, 2023
Pertussis, commonly known as whooping cough is a severe respiratory disease caused by the bacterium, Bordetella pertussis. Despite widespread vaccination, pertussis resurgence has been observed globally.
Hiroki Suyama   +4 more
doaj   +1 more source

Development of a qualitative assay for screening of Bordetella pertussis isolates for pertussis toxin production. [PDF]

open access: yes, 2017
Bordetella pertussis infection has been increasing in the US, with reported cases reaching over 50,000 in 2012, a number last observed in the 1950s. Concurrently, B. pertussis lacking the pertactin protein, one of the immunogens included in the acellular
Hong Ju   +5 more
core   +1 more source

Simultaneous Determination of Antibodies to Pertussis Toxin and Adenylate Cyclase Toxin Improves Serological Diagnosis of Pertussis [PDF]

open access: yes, 2021
Serological diagnosis of pertussis is mainly based on anti-pertussis toxin (PT) IgG antibodies. Since PT is included in all acellular vaccines (ACV), serological assays do not differentiate antibodies induced by ACVs and infection.
Peter Sebo   +5 more
core   +1 more source

Analysis of Bordetella pertussis pertactin and pertussis toxin types from Queensland, Australia, 1999–2003

open access: yesBMC Infectious Diseases, 2006
Background In Australia two acellular Bordetella pertussis vaccines have replaced the use of a whole cell vaccine. Both of the licensed acellular vaccines contain the following three components; pertussis toxoid, pertussis filamentous haemagglutinin and ...
Slack Andrew T, Byrne Shane
doaj   +1 more source

The ins and outs of pertussis toxin [PDF]

open access: yesThe FEBS Journal, 2011
Pertussis toxin, produced and secreted by the whooping cough agentBordetella pertussis, is one of the most complex soluble bacterial proteins. It is actively secreted through theB. pertussiscell envelope by the Ptl secretion system, a member of the widespread type IV secretion systems. The toxin is composed of five subunits (named S1 to S5 according to
Camille, Locht   +2 more
openaire   +2 more sources

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