Results 41 to 50 of about 29,628 (214)
Changes in genetic diversity of the Bordetella pertussis population in Serbia between 1953 and 2011 [PDF]
Archives of Biological Sciences, 2014 Mass vaccination has significantly reduced the incidence of pertussis, however, the disease is re-emerging, even in some countries with high vaccination coverage. In Serbia, whole cell pertussis vaccine was introduced in 1957. To monitor changes
Plješa Tatjana +5 more
doaj +1 more source
Pasteurian Contributions to the Study of Bordetella pertussis Toxins
Toxins, 2023 As a tribute to Louis Pasteur on the occasion of the 200th anniversary of his birth, this article summarizes the main contributions of scientists from Pasteur Institutes to the current knowledge of toxins produced by Bordetella pertussis.
Camille Locht
doaj +1 more source
Nurr1 Orchestrates Claustrum Development and Functionality
Advanced Science, EarlyView.Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Genomics of Bordetella pertussis toxins
International Journal of Medical Microbiology, 2000 Bordetella pertussis, the etiologic agent of whooping cough, produces numerous toxins including pertussis toxin (PTX), adenylate cyclase toxin (AC), dermonecrotic toxin (DNT) and tracheal cytotoxin (TCT). PTX is composed of five different subunits organised in a typical A-B type structure of which the A part possesses an enzymatic ADP ...
R, Antoine, D, Raze, C, Locht
openaire +2 more sources
Single Amino Acid Polymorphisms of Pertussis Toxin Subunit S2 (PtxB) Affect Protein Function. [PDF]
PLoS ONE, 2015 Whooping cough due to Bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations.
Scott H Millen +7 more
doaj +1 more source
Advanced Science, EarlyView.An Automated ex vivo culture system BaSIC, tailored for SCN slices and cell culture, which automates medium exchange and ensures a stable internal environment is developed. BaSIC enables real‐time observation of tissue/cell responses to diverse but programmed stimuli.
Kui Han +7 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2022 To determine the estimated pertussis incidence in adults and the need for a booster dose by detecting pertussis and diphtheria antibody levels in adults in Shaanxi province, China. Blood samples were collected from healthy individuals aged 18–59 years in
Chao Zhang +8 more
doaj +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
PLANTS, PEOPLE, PLANET, EarlyView.Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source
CONSTRUCTION OF RECOMBINANT ATTENUATED BORDETELLA PERTUSSIS BACTERIA OF PTXP3 GENOTYPE
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Aim. The construction of recombinant attenuated Bordetella pertussis bacteria of ptxP3 genotype and its genetic and biological stability characteristics. Materials and methods.
E. G. Semin +3 more
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Small mutations in Bordetella pertussis are associated with selective sweeps. [PDF]
PLoS ONE, 2012 Bordetella pertussis is the causative agent of pertussis, a highly contagious disease of the human respiratory tract. Despite high vaccination coverage, pertussis has resurged and has become one of the most prevalent vaccine-preventable diseases in ...
Marjolein van Gent +4 more
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