Results 151 to 160 of about 18,673,205 (171)

Development of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs [PDF]

open access: yesJournal of Virological Methods, 2011
Porcine endogenous retroviruses (PERV) represent a risk for xenotransplantation using pig cells, tissues or organs. PERV-A and PERV-B are present in the genome of all pigs and both infect human cells in vitro.
Ralf Reinhard Toenjes   +2 more
exaly   +2 more sources

The Porcine Endogenous Retrovirus Long Terminal Repeat Contains a Single Nucleotide Polymorphism That Confers Distinct Differences in Estrogen Receptor Binding Affinity between PERV A and PERV B/C Subtypes [PDF]

open access: yesVirology, 2001
Porcine endogenous retroviruses (PERV) have been shown to have zoonotic potential, both in vitro and in vivo. Once integrated into the host cell genome activation of the proviral genes is ultimately dependent upon transactivation of the long terminal ...
Langford, Gillian, Quinn, Gary
exaly   +2 more sources

Long‐term effects of PERV‐specific RNA interference in transgenic pigs

open access: yesXenotransplantation, 2012
Background: Porcine endogenous retroviruses (PERVs) represent a risk of xenotransplantation using porcine cells, tissues, or organs, as they are integrated in the porcine genome and have been shown to be able to infect human cells in vitro.
Bjoern Petersen, Joachim Denner
exaly   +2 more sources

Functional hierarchy of two L domains in porcine endogenous retrovirus (PERV) that influence release and infectivity [PDF]

open access: yesVirology, 2008
The porcine endogenous retrovirus (PERV) Gag protein contains two late (L) domain motifs, PPPY and P(F/S)AP. Using viral release assays we demonstrate that PPPY is the dominant L domain involved in PERV release.
Carolyn A Wilson, Daniel R Salomon
exaly   +2 more sources

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