Additional file 1 of Analysis of PERV-C superinfection resistance using HA-tagged viruses
Additional file 1: Figure S1. AA-sequence and secondary structure analysis of PERV-C(5683) (KY352351.2) (PSIPRED [47]). A PSIPRED analysis taken as basis for the HA-tag introduction. Black arrows indicate positions of HA-tag integration. Env specific domains like SP, variable regions and PRR are framed in black.
Flecks, Merle +4 more
openaire +1 more source
Indicators to identify cancer screening providers with suboptimal case detection: A scoping review
What's new? Quality control of cancer screening programs is essential to maintaining high public health standards. Here, the authors reviewed monitoring of case detection in cervical and colorectal cancer screening programs in Europe, and evaluated its effectiveness. They analysed 20 different measures used for this purpose and showed that many of them
Jiayao Lei +5 more
wiley +1 more source
Distribution Of Porcine Endogenous Retrovirus (PERV) Variants In Domestic And Feral Pig [PDF]
Xenotransplantation is considered an alternative to allotransplantation to relieve the current shortage of human organs. Due to their similar size and physiology, the organs of pigs are of particular interest for this purpose. Endogenous retroviruses are
Acharya, Rashmi
core +1 more source
Additional file 3 of Analysis of PERV-C superinfection resistance using HA-tagged viruses
Additional file 3: Figure S3. pLDDT scores obtained after AlphaFold prediction. Scores for all predicted models (rank 1–5) of PERV-C(5683) as well as for PERV-C(5683)-HA viruses are shown. Residues with pLDDT ≥ 90 have very high model confidence, residues with 90 > pLDDT ≥ 70 are classified as confident.
Flecks, Merle +4 more
openaire +1 more source
Identifying Subcellular Structure Components in Escherichia Coli by Crosslinking and SEC‐MS
ABSTRACT Cells are comprised of a broad spectrum of structures that compartmentalize biochemical and signaling mechanisms. These structures can be comprised of many biomolecules, but especially lipids, proteins, and nucleic acids. Techniques are limited to quantify or discover new subcellular structures.
Rachel A. Victor +3 more
wiley +1 more source
Additional file 4 of Analysis of PERV-C superinfection resistance using HA-tagged viruses
Additional file 4: Figure S4. Control of proviral integration of PERV-C(5683)-HA after superinfection. Genomic DNA of superinfected cells (56 days p.i.) was used for envC (A) and envC-HA (B) specific PCRs. Lane 1: ST-IOWA (ctr−), lane 2: PERV-C(5683) positive ST-IOWA cells, lane 3: ST-IOWA infected with SP-HA (ctr1+), lane 4: ST-IOWA positive for PERV ...
Flecks, Merle +4 more
openaire +1 more source
Permanent Revenue in an Energy‐Exporting Economy: A New Test for Fiscal Equilibrium
ABSTRACT Fiscal disequilibrium arises when permanent expenditures (PEXP) exceed permanent revenue (PREV), a frequent risk in energy‐exporting economies reliant on volatile windfall revenues. However, existing research lacks a clear measure of these concepts and an empirical test for fiscal equilibrium.
Akeem Rahaman, Scott Mark Romeo Mahadeo
wiley +1 more source
Xenoperfusion—The Transformative Role of Machine Perfusion in Xenotransplantation
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Florian Huwyler +3 more
wiley +1 more source
Presence of Porcine Endogenous Retrovirus C in Domestic Pigs in Kansas [PDF]
There is currently a shortage of organs available to perform allotransplants in humans, prompting the exploration of xenotransplantation as an alternative.
Gillock, Eric T., Welton, Avery
core +1 more source
IDENTIFICATION OF WHOLE GENOMES OF ENDOGENOUS RETROVIRUSES IN SIBERIAN MINIATURE PIGS
Study of the populational dynamics of Siberian miniature pigs for the gag and env loci of endogenous pig retroviruses is reported. Currently, the frequency of carriers of types A, B, and C of PERV genomes in minipigs is high.
R. B. Aitnazarov +4 more
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