Modular strategies for PET imaging agents [PDF]
Current Opinion in Chemical Biology, 2010 In recent years, modular and simplified chemical and biological strategies have been developed for the synthesis and implementation of positron emission tomography (PET) radiotracers. New developments in bioconjugation and synthetic methodologies, in combination with advances in macromolecular delivery systems and gene-expression imaging, reflect a ...
Hooker, Jacob M
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A generator-produced gallium-68 radiopharmaceutical for PET imaging of myocardial perfusion. [PDF]
PLoS ONE, 2014 Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifies ...
Vijay Sharma +6 more
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Positron Emission Tomographic Imaging of Copper 64– and Gallium 68–Labeled Chelator Conjugates of the Somatostatin Agonist Tyr-Octreotate [PDF]
Molecular Imaging, 2014 The bifunctional chelator and radiometal have been shown to have a direct effect on the pharmacokinetics of somatostatin receptor (SSTR)-targeted imaging agents.
Jessie R. Nedrow +5 more
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PET/CT for Predicting Occult Lymph Node Metastasis in Gastric Cancer
Current Oncology, 2022 A portion of gastric cancer patients with negative lymph node metastasis at an early stage eventually die from tumor recurrence or advanced metastasis.
Danyu Ma +4 more
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The progress of PET/MRI in clinical management of patients with pancreatic malignant lesions
Frontiers in Oncology, 2023 Recently, the morbidity and mortality of pancreatic cancer have been increasing year by year. Because of its deep anatomical location and because most presented patients often suffer from abdominal pain or jaundice, it is difficult to diagnose pancreatic
Jindan Li +8 more
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PET Imaging in Animal Models of Alzheimer’s Disease
Frontiers in Neuroscience, 2022 The successful development and translation of PET imaging agents targeting β-amyloid plaques and hyperphosphorylated tau tangles have allowed for in vivo detection of these hallmarks of Alzheimer’s disease (AD) antemortem.
Baosheng Chen +6 more
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On the Dissociation Pathways of Copper Complexes Relevant as Pet Imaging Agents
SSRN Electronic Journal, 2022 Several bifunctional chelators have been synthesized in the last years for the development of new 64Cu-based PET agents for in vivo imaging. When designing a metal-based PET probe, it is important to achieve high stability and kinetic inertness once the radioisotope is coordinated. Different competitive assays are commonly used to evaluate the possible
Uzal-Varela, Rocío +8 more
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Development of [124/125I]IAZA as a New Proteinopathy Imaging Agent for Alzheimer’s Disease
Molecules, 2023 Radioiodinated imaging agents for Aβ amyloid plaque imaging in Alzheimer’s disease (AD) patients have not been actively pursued. Our previous studies employed the “diaza” derivatives [11C]TAZA and [18F]flotaza in order to develop successful positron ...
Thrisha T. Reddy +5 more
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The Integration of Positron Emission Tomography With Magnetic Resonance Imaging [PDF]
, 2008 A number of laboratories and companies are currently exploring the development of integrated imaging systems for magnetic resonance imaging (MRI) and positron emission tomography (PET).
Cherry, Simon R. +2 more
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Research Progress of PET Traces for Alzheimer’s Disease
Journal of Isotopes, 2014 Alzheimer’s disease (AD) is unknown cause progressive degenerative diseases of central nervous system. It is a serious threat to the health of the elderly people. The diagnosis is mainly based on pathological examination after death.
TANG Cai-hua1，2;HU Kong-zhen1;TANG Gang-hua1
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