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Petunidin, a B-ring 5′-O-Methylated Derivative of Delphinidin, Stimulates Osteoblastogenesis and Reduces sRANKL-Induced Bone Loss [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Several lines of evidence suggest that oxidative stress is one of the key pathogenic mechanisms of osteoporosis. We aimed to elucidate the bone protective effects of petunidin, one of the most common anthocyanidins, considering its potent antioxidative activity. Petunidin (>5 μg/mL) significantly inhibited osteoclastogenesis and downregulated c-fos,
Marlena Kruger   +2 more
exaly   +7 more sources

The biological activity of the wine anthocyanins delphinidin and petunidin is mediated through Msn2 and Msn4 in Saccharomyces cerevisiae [PDF]

open access: yesFEMS Yeast Research, 2010
Polyphenols are considered to be responsible for some of the health benefits derived from the consumption of red wine. These protective effects might probably be explained in the context of the xenohormesis theory that considers plant metabolites as interspecific chemical signals.
M TERESA Escribano-Bailón   +2 more
exaly   +8 more sources
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Targeting NOX 4 by petunidin improves anoxia/reoxygenation-induced myocardium injury

European Journal of Pharmacology, 2020
Oxidative stress is the key factor of myocardial ischemia-reperfusion injury (MIRI). Anthocyanins are considered to be effective anti-oxidants. In this study, we observed the anti-MIRI effect of petunidin, one member of anthocyanins, and further explored its mechanism.
Chunli Yang, Xinyong Cai, Lang Hong
exaly   +3 more sources

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