Results 31 to 40 of about 2,561 (146)

Pexophagy: A Model for Selective Autophagy

, 2020
The removal of damaged or superfluous organelles from the cytosol by selective autophagy is required to maintain organelle function, quality control and overall cellular homeostasis.
Kyla Germain, Peter K. Kim
core   +1 more source

Pexophagy suppresses ROS-induced damage in leaf cells under high-intensity light

Nature Communications, 2022
Pexophagy plays a pivotal role in the selective removal of ROS-generating peroxisomes, which protects plants from oxidative damage during photosynthesis under high-intensity light.
Kazusato Oikawa, Shino Goto-Yamada, Yasuko Hayashi, Daisuke Takahashi, Yoshitaka Kimori, Michitaro Shibata, Kohki Yoshimoto, Atsushi Takemiya, Maki Kondo, Kazumi Hikino, Akira Kato, Keisuke Shimoda, Haruko Ueda, Matsuo Uemura, Keiji Numata, Yoshinori Ohsumi, Ikuko Hara-Nishimura, Shoji Mano, Kenji Yamada, Mikio Nishimura   +19 more
doaj   +1 more source

Enhancement of xylanase expression by Komagataella phaffii through pexophagy inhibition

Biotechnology & Biotechnological Equipment, 2019
Xylanase is widely used in agriculture and food industry. To increase heterologous xylanase expression by Komagataella phaffii under the condition of mixed carbon source feeding, the atg30 gene was knocked out from this yeast to inhibit pexophagy for ...
Taiyu Liu, Yixin Zhao, Jianguo Zhang, Jining Zhang   +3 more
doaj   +1 more source

Autophagy as a Survival Strategy for Eukaryotic Microbes Living in the Phyllosphere

Frontiers in Plant Science, 2022
Autophagy is an intracellular degradation process that is highly conserved among eukaryotes at the molecular level. The process was originally revealed in the budding yeast, but the physiological role of autophagy in yeast cells had remained unknown as ...
Kosuke Shiraishi, Yasuyoshi Sakai
doaj   +1 more source

Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists

Frontiers in Cell and Developmental Biology, 2022
One peculiarity of protists belonging to classes Kinetoplastea and Diplonemea within the phylum Euglenozoa is compartmentalisation of most glycolytic enzymes within peroxisomes that are hence called glycosomes.
Diego Andrade-Alviárez, Alejandro D. Bonive-Boscan, Ana J. Cáceres, Wilfredo Quiñones, Melisa Gualdrón-López, Michael L. Ginger, Paul A. M. Michels   +6 more
doaj   +1 more source

A mammalian pexophagy target

, 2015
Protein ubiquitylation in mammals is known to trigger selective autophagy of peroxisomes through a process termed pexophagy. The physiological peroxisomal target for pexophagy-related ubiquitylation has been controversial, but two studies have now ...
Suresh Subramani, Subramani, Suresh
core   +1 more source

The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast

eLife, 2022
Autophagy receptor (or adaptor) proteins facilitate lysosomal destruction of various organelles in response to cellular stress, including nutrient deprivation. To what extent membrane-resident autophagy receptors also respond to organelle-restricted cues
Houqing Yu, Roarke A Kamber, Vladimir Denic   +2 more
doaj   +1 more source

The Peroxisome-Autophagy Redox Connection: A Double-Edged Sword?

Frontiers in Cell and Developmental Biology, 2021
Peroxisomes harbor numerous enzymes that can produce or degrade hydrogen peroxide (H2O2). Depending on its local concentration and environment, this oxidant can function as a redox signaling molecule or cause stochastic oxidative damage. Currently, it is
Hongli Li, Celien Lismont, Iulia Revenco, Mohamed A. F. Hussein, Mohamed A. F. Hussein, Cláudio F. Costa, Marc Fransen   +6 more
doaj   +1 more source

DcH3.3 and DcNAC1 Regulate the Expression of UGT73A93 Involved in the Changes in Flower Colour and Fungal Resistance in Carnation

Plant Biotechnology Journal, EarlyView.
ABSTRACT Carnation (Dianthus caryophyllus) contains abundant flavonoid glycosides (FGs), which are important natural functional and colour components. However, there are few reports on the modification of UDP‐glycosyltransferases (UGTs) in relation to flavonoids in carnation.
Xuhong Zhou, Qirui Xiong, Yue Zhang, Xiumei Yang, Siyuan Zhang, Yanxia Tao, Xiaomi Yang   +6 more
wiley   +1 more source

Assays to Monitor Pexophagy in Yeast

, 2017
Pexophagy is a selective autophagy process that degrades damaged and/or superfluous peroxisomes in the yeast vacuole or in mammalian lysosomes. The molecular mechanisms of pexophagy are well studied in yeast.
Wang, W, Subramani, S, S. Subramani, W. Wang   +3 more
core   +1 more source