Results 41 to 50 of about 4,214 (236)

Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae [PDF]

, 2012
Peroxisomes undergo rapid, selective autophagic degradation (pexophagy) when the metabolic pathways they contain are no longer required for cellular metabolism.
Alison M Motley, Aoki, Baba, Barnard, Bartel, Bellu, Bellu, Bernales, Campbell, Chang, de Duve, Dunn, Ewald H Hettema, Farre, Fromont-Racine, Gietz, Hara-Kuge, Harding, Harding, Hettema, Hettema, Hohfeld, Hutchins, Ito, James M Nuttall, Johansen, Kanki, Kanki, Kim, Kim, Kirkin, Knoblach, Kondo-Okamoto, Kraft, Levine, Lynch-Day, Ma, Manjithaya, Manjithaya, Mao, Mao, Mitchener, Mizushima, Motley, Motley, Munck, Nakatogawa, Noda, Noda, Noda, Novak, Okamoto, Pankiv, Ravikumar, Rich, Rucktaschel, Rucktaschel, Sakai, Scott, Shintani, Snapp, Suzuki, Suzuki, Suzuki, Suzuki, Takeshige, Tower, Uetz, van Zutphen, van Zutphen, Vida, Vojtek, Weidberg, Wild, Xie, Yorimitsu, Yorimitsu, Yu   +77 more
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Modulation of plant autophagy during pathogen attack [PDF]

, 2017
In plants, the highly conserved catabolic process of autophagy has long been known as a means of maintaining cellular homeostasis and coping with abiotic stress conditions. Accumulating evidence has linked autophagy to immunity against invading pathogens,
Bozkurt, Tolga O., Duggan, Cian, Leary, Alexandre Y, Pandey, Pooja, Salguero Linares, Jose, Sanguankiattichai, Nattapong, Savage, Zachary D, Segretin, Maria Eugenia, Tumtas, Yasin, Yow, Rui Jin   +9 more
core   +1 more source

A mammalian pexophagy target [PDF]

Nature Cell Biology, 2015
Protein ubiquitylation in mammals is known to trigger selective autophagy of peroxisomes through a process termed pexophagy. The physiological peroxisomal target for pexophagy-related ubiquitylation has been controversial, but two studies have now identified the protein PEX5 as the real candidate.
openaire   +4 more sources

The selectivity and specificity of autophagy in drosophila [PDF]

, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou, Clark, Contamine, Deng, Dezelee, Finley, Fouillet, Goto, Kadandale, McPhee, Midorikawa, Nezis, Nisoli, Novak, Orvedahl, Pankiv, Park, Rello-Varona, Schweers, Shoji, Simonsen, Tian, Webb, Wild, Wyers, Yu, Yu, Ziviani   +27 more
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BNIP3L/NIX regulates both mitophagy and pexophagy

The EMBO Journal, 2022
AbstractMitochondria and peroxisomes are closely related metabolic organelles, both in terms of origin and in terms of function. Mitochondria and peroxisomes can also be turned over by autophagy, in processes termed mitophagy and pexophagy, respectively. However, despite their close relationship, it is not known if both organelles are turned over under
Wilhelm, Léa P, Zapata‐Muñoz, Juan, Villarejo‐Zori, Beatriz, Pellegrin, Stephanie, Freire, Catarina Martins, Toye, Ashley M, Boya, Patricia, Ganley, Ian G   +7 more
openaire   +5 more sources

Endoplasmic Reticulum–Mitochondria Contacts Are Required for Pexophagy in

Contact, 2019
Peroxisomes play important roles in lipid metabolism. Surplus or damaged peroxisomes can be selectively targeted for autophagic degradation, a process termed pexophagy . Maintaining a proper level of pexophagy is critical for cellular homeostasis.
Xu Liu, Xin Wen, Daniel J. Klionsky
doaj   +1 more source

The different facets of organelle interplay - an overview of organelle interactions [PDF]

, 2015
ReviewThis Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permission.Membrane-bound organelles such as mitochondria, peroxisomes, or the endoplasmic reticulum (ER) create distinct ...
Costello, JC, Godinho, Luis F., Islinger, MI, Schrader, M   +3 more
core   +1 more source

Atg26-mediated pexophagy and fungal phytopathogenicity [PDF]

Autophagy, 2009
Colletotrichum orbiculare is a plant pathogenic fungus that causes disease on cucumber plants. A homologue of ATG26 (CoATG26) was identified as the gene involved in pathogenesis. The peroxisomes are degraded via pexophagy during formation of an infection structure called the appressorium of C. orbiculare.
Yoshitaka, Takano, Makoto, Asakura, Yasuyoshi, Sakai   +2 more
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The making of a mammalian peroxisome, version 2.0: mitochondria get into the mix [PDF]

, 2017
This is the author accepted manuscript. The final version is available from Nature Publishing Group via the DOI in this record.A recent report from the laboratory of Heidi McBride (McGill University) presents a role for mitochondria in the de novo ...
A Bagattin, A Sood, A Sugiura, A Sugiura, A van der Zand, AC Muntau, AM Motley, AM Motley, AM Pickrell, B Knoblach, C Williams, D Hoepfner, D Matheoud, E Area-Gomez, E Area-Gomez, E Braschi, EH Hettema, FC Klouwer, G Agrawal, GL McLelland, GL McLelland, HK Delille, HW Platta, J Berger, J Koch, JA Kiel, JE Vance, JE Vance, JE Vance, JJ Smith, JL Costello, K Knoops, KA Sacksteder, Luca Pellegrini, M Giacomello, M Honsho, M Neuspiel, M Schrader, M Schrader, M Schrader, Michael Schrader, MS Herrera-Cruz, NA Bonekamp, NE Braverman, PB Lazarow, PK Kim, R Erdmann, R Hua, R Hua, R Rucktaschel, R Stoica, RJ Wanders, S Caielli, S Goldfischer, S Vyas, S Yamashita, SJ Gould, SJ Huybrechts, T Matsuzaki, V Soubannier, W Yuan   +60 more
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Michael J Clague: mitophagy, pexophagy, & metabolism

Life Science Alliance, 2023
Michael J Clague is a Professor of Molecular and Cellular Physiology at The University of Liverpool, Institute of Systems, Molecular and Integrative Biology. We asked him about his recent paper published in Life Science Alliance (LSA) and his experience in science thus far.
openaire   +2 more sources