Results 51 to 60 of about 2,719 (141)

Regulatory Mechanism of Peroxisome Number Reduction Caused by FgPex4 and FgPex22-like Deletion in Fusarium graminearum

Journal of Fungi, 2023
Peroxisomes are single-membrane-bound organelles that play critical roles in eukaryotic cellular functions. Peroxisome quantity is a key factor influencing the homeostasis and pathogenic processes of pathogenic fungi.
Chunjie Liu, Zhuoyu Bi, Hao Xu, Renjie Zhang, Jiayi Wang, Yuancun Liang, Li Zhang, Jinfeng Yu   +7 more
doaj   +1 more source

Regulation of autophagy‐mediated pathways by diet, physical activity, and sleep in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract Alzheimer's disease (AD) is a progressive, age‐related, neurodegenerative disorder marked by cognitive decline, memory loss, and accumulation of amyloid beta (Aβ) plaques and tau tangles. A key feature of AD is impaired protein homeostasis, often driven by autophagy dysfunction.
Ajish Ariyath, Zoe Mputhia, Christopher Dougherty, Bushra Kaleelur Rahuman, W. M. A. D. Binosha Fernando, Belinda Brown, Samantha L. Gardener, Stephanie R. Rainey‐Smith, Ralph Martins, Prashant Bharadwaj   +9 more
wiley   +1 more source

Peroxisome degradation in mammals: mechanisms of action, recent advances, and perspectives

Frontiers in Physiology, 2013
Peroxisomes are remarkably dynamic organelles that participate in a diverse array of cellular processes, including the metabolism of lipids and reactive oxygen species.
Marcus eNordgren, Bo eWang, Oksana eApanasets, Marc eFransen   +3 more
doaj   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

Pexophagy and peroxisomal protein turnover in plants

, 2016
Peroxisomes are dynamic, vital organelles that sequester a variety of oxidative reactions and their toxic byproducts from the remainder of the cell.
Young, Pierce G., Bartel, Bonnie
core   +1 more source

STED super-resolution microscopy unveils the dynamics of Atg30 on yeast Pex3-labeled peroxisomes

iScience
Summary: Peroxisomes are dynamic organelles with important metabolic functions. Yeast Pex3 is a multifunctional membrane protein aiding in peroxisomal biogenesis, inheritance, and degradation (pexophagy), by interacting with process-specific factors ...
Eline M.F. de Lange, Frank N. Mol, Ida J. van der Klei, Rifka Vlijm   +3 more
doaj   +1 more source

Assays to Monitor Pexophagy in Yeast

, 2017
Pexophagy is a selective autophagy process that degrades damaged and/or superfluous peroxisomes in the yeast vacuole or in mammalian lysosomes. The molecular mechanisms of pexophagy are well studied in yeast.
Wang, W, Subramani, S, S. Subramani, W. Wang   +3 more
core   +1 more source

Cadmium induces reactive oxygen species-dependent pexophagy in Arabidopsis leaves [PDF]

, 2019
Cadmium treatment induces transient peroxisome proliferation in Arabidopsis leaves. To determine whether this process is regulated by pexophagy and to identify the mechanisms involved, we analysed time course-dependent changes in ATG8, an autophagy ...
Expósito Rodríguez, Marino, Díaz, Isabel, Diaz Rodriguez, Isabel, Romero-Puertas, María C., Laureano-Marín, Ana M, Ana M. Laureano‐Marín, Philip M. Mullineaux, Exposito-Rodriguez, Marino, Rodríguez Serrano, María, Sandalio, Luisa M., María C. Romero‐Puertas, Collado-Arenal, Aurelio M., Laureano-Marín, Ana M., Mullineaux, Philip M., Santamaría, M Estrella, Santamaría Fernández, María Estrella, Cecilia Gotor, María Rodríguez‐Serrano, M. Estrella Santamaría, Calero-Muñoz, Nieves, Adela Olmedilla, Collado-Arenal, Aurelio M, Olmedilla, Adela, Calero Muñoz, Nieves, Collado Arenal, Aurelio M., Mullineaux, P.M., Laureano Marín, Ana M., Aurelio M. Collado‐Arenal, Mullineaux, Philip M, Santamaría, María Estrella, Isabel Díaz, Gotor, Cecilia, Romero Puertas, María C., Marino Exposito‐Rodriguez, Rodríguez-Serrano, María, Sandalio, Luisa M, Nieves Calero‐Muñoz, Romero-Puertas, María C, Luisa M. Sandalio   +38 more
core   +1 more source

Lipid Autophagy: An Idea for the Treatment of Diabetic Nephropathy With Ginseng and Its Active Compounds

eFood, Volume 6, Issue 6, December 2025.
In light of the steadily increasing incidence of diabetic nephropathy (DN), this review explores the potential of edible natural products to slow disease progression, addressing the limitations of conventional clinical drug therapies. Key findings show that ginsenosides, the active compounds in edible ginseng, regulate lipid autophagy, reducing ...
Rui Zhang, Xushan Lan, Chenguang Wu, Jingjing Wang, Chengqian Yin, Lifan Wang, Peng Liu, Ping Li   +7 more
wiley   +1 more source

New aspects of USP30 biology in the regulation of pexophagy [PDF]

, 2019
Mitochondria and peroxisomes have a number of features in common: they each play interconnected roles in fatty acid and reactive oxygen species (ROS) metabolism and, once damaged, need to be removed by specialized autophagic mechanisms, termed mitophagy ...
Jardine, Jane, Clague, Michael J, Kallinos, Andreas, Rusilowicz-Jones, Emma V, Urbe, Sylvie, Marcassa, Elena   +5 more
core   +1 more source